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Updated: Feb 14, 2026

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膜上皮表表型的Wnt依赖调节和在人类原始细胞类细胞中的屏障功能

Yu-Che Lin1, Miki Igarashi2, Yasuyuki Sakai2

  • 1Department of Bioengineering, Graduate School of Engineering, The University of Tokyo, Tokyo, Japan.

Biochemical and biophysical research communications
|February 12, 2026
PubMed
概括

这项研究开发了一种空气-液体接口 (ALI) 培养,以建模膜再生,表明YAC(-) 条件保持了具有优越屏障功能和修复的平衡AT1/AT2状态,而β-catenin抑制促进了AT1特征.

关键词:
空气-液体接口培养气泡膜系的可塑性 气泡膜系的可塑性表面上皮质的修复.通过皮质的电阻电阻.在 Wnt 信号调制中.抑制β-catenin的抑制作用

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