超密集的氧化陶闪器用于正子发射断层扫描
Akram Hamato1, Daehee Lee2, Ryosuke Ota3
1Biomedical Engineering, University of California Davis, 451 East Health Sciences Drive, Davis, California, 95616, United States.
新的氧化 (Lu2O3) 陶闪器显示出对正电子发射断层扫描 (PET) 的前景. (Lu,Y) 2O3:La陶具有与Lu2O3:Yb可比的定时分辨率,因此适合用于飞行时间PET成像.
科学领域:
- 材料科学 材料科学 材料科学
- 核仪器仪表 核仪器仪表 核仪器仪表
- 医疗成像医学成像
背景情况:
- 氧化 (Lu2O3) 具有高密度,非常适合在正电子发射断层扫描 (PET) 中检测511 keV光子.
- 结晶生长的挑战和缓慢的衰变时间限制了Lu2O3的PET应用.
- 陶加工和兴奋剂的进步使得透明的Lu2O3陶具有更好的发光.
研究的目的:
- 为了评估Lu2O3:Yb和一个新的 (Lu,Y) 2O3:La陶闪电器的性能.
- 评估它们适用于正子发射断层扫描 (PET) 应用的适用性,特别是飞行时间 (TOF) PET.
主要方法:
- 陶盘的制造和切成3×3×5mm3的样品.
- 使用光倍增管 (PMT) 和光倍增器 (SiPM) 评估衰变时间,能量分辨率和巧合时间分辨率 (CTR).
- 来自22Na源的511 keV光子的辐射和与参考LYSO探测器相对应的巧合测量.
主要成果:
- (Lu,Y) 2O3:La样本显示出三倍指数衰变,以缓慢成分 (1379.31515.6 ns) 为主,具有最佳能量分辨率 (15.4%) 和CTR (237.9 ps FWHM).
- 2O3:Yb样本表现出快速衰变 (1.6 ns) 和CTR值从237.9 ps到261.4 ps的FWHM,但有难以区分的光点.
- 尽管衰变速度较慢,但 (Lu,Y) 2O3:La由于更高的光输出率,实现了与Lu2O3:Yb相比的CTR,抵消了衰变时间的缺点.
结论:
- (Lu,Y) 2O3:La陶闪器显示出对PET成像的巨大潜力.
- 这些材料对推进飞行时间 (TOF) PET技术特别有希望.
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