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Updated: Feb 14, 2026

Biochemical Assays for Analyzing Activities of ATP-dependent Chromatin Remodeling Enzymes
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Published on: October 25, 2014

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人类BAF染色体重塑器处理由先驱转录因子OCT4-SOX2结合的核细胞

Joscha Weiss1, Luca Vecchia2, David Domjan3

  • 1Institute for Cancer Research (ISREC), Swiss Federal Institute of Technology Lausanne (EPFL), Station 19, CH-1015 Lausanne, Switzerland; Friedrich Miescher Institute for Biomedical Research, Fabrikstrasse 24, 4058 Basel, Switzerland; University of Basel, Petersplatz 10, 4001 Basel, Switzerland.

Molecular cell
|February 12, 2026
PubMed
概括

像OCT4-SOX2这样的先驱转录因子 (TF) 与核细胞体上的BAF复合体相互作用. BAF复合体使用两个方向,影响TF结合,并可能改变染色质重塑方向.

关键词:
在BAF中,BAF是BAF.经合组织CT4这就是SOX2的含量.在 SWI/SNF 中.染色体重塑剂的使用方法低温电磁波冷却器 (Cryo-EM) 是一个非常好的方法.基因调节 基因调节 基因调节核子组是核子组中的一个.开创了开拓者TFs.单分子FRETET是一种单分子FRET.

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