内源性与外源性Candida Endophthalmitis:临床特征,危险因素,治疗方法和视觉结果
Sujin Kang1, Thomas A Albini1, Nicolas A Yannuzzi1
1Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, USA.
American journal of ophthalmology
|February 12, 2026
概括
根据感染源,Candida endophthalmitis具有不同的临床特征和结果. 内源病例,通常来自C. albicans,具有更好的视觉结果,而外源病例更难治疗.
科学领域:
- 眼科医生 眼科 眼科
- 传染性疾病 传染性疾病
- 医学真菌学 医学真菌学
背景情况:
- 坎迪达内眼炎是一种严重的眼内感染.
- 了解其临床特征对于有效管理至关重要.
研究的目的:
- 分析Candida endophthalmitis的临床特征,危险因素,治疗方法和视觉结果.
- 要区分内源和外源感染源.
主要方法:
- 追溯46名患有培养证明的Candida endophthalmitis的患者病例系列.
- 收集的数据包括人口统计,风险因素,治疗和视力敏度.
- 眼内培养证实了诊断.
主要成果:
- C. albicans 是最常见的病因,特别是在内源性病例中.
- 与住院,静脉注射药物使用和恶性瘤相关的内源性感染.
- 与眼部手术相关的外部感染.
- 视网膜脱落是最常见的并发症.
- 对于内源性感染,视觉结果明显更好.
结论:
- 根据感染源,Candida endophthalmitis的表现不同.
- 内生病例 (通常是C. albicans) 的视觉预后更好.
- 外源病例 (通常是非白种) 更难以治疗,结果更差.
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