血液静止剂在周围外科手术:系统性审查和元分析
Fabio Genchi1, Juan Antonio Blaya Tárraga2, Cristina Palma Carrió2
1Private Practice, Bari, Italy.
Journal of endodontics
|February 12, 2026
概括
静血剂在周围手术中显示出良好的疗效,用于控制出血. 然而,没有发现药物之间或它们对预后或患者相关因素的影响有显著差异.
科学领域:
- 牙周内科医院 牙周内科医院 牙周内科医院
- 在口腔外科手术.
- 基于证据的牙科.
背景情况:
- 在外科手术期间出血是周围手术的一个挑战.
- 在这些手术中,用于控制出血的血液静止剂.
- 了解它们的有效性和对预后的影响至关重要.
研究的目的:
- 系统地审查和元分析在周围外科手术中药物的静血疗效.
- 评估这些药物对治疗预后的影响.
- 调查患者和牙相关的临床变量的作用.
主要方法:
- 按照PRISMA指南进行系统审查和元分析.
- 搜索了PubMed,Scopus,科学网和科克兰图书馆,直到2024年10月.
- 包括随机对照试验 (RCT) 和对照临床试验 (CCT),预后随访>12个月.
主要成果:
- 包括10项研究 (388颗牙);平均静血疗效率为63±6.6%.
- 在元分析和元回归中,大多数药物之间没有发现统计学上显著的差异.
- 网络元分析显示,上腺素和化优于原蛋白 (p<0.05);吸烟趋于显著 (p=0.074).
结论:
- 经过评估的止血剂显示出良好的手术内血流控制功效.
- 在代理人之间或与预后的关系之间没有发现统计学上显著的差异.
- 血静疗效与患者或牙相关的变量之间没有发现任何关联.
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