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Updated: Feb 14, 2026

Modeling Age-Associated Neurodegenerative Diseases in Caenorhabditis elegans
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Modeling Age-Associated Neurodegenerative Diseases in Caenorhabditis elegans

Published on: August 15, 2020

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镜片衰老和疾病:分子机制,功能后果和药理学影响

Xingjun Fan1, Vincent M Monnier2

  • 1Department of Cellular Biology and Anatomy, Medical College of Georgia at Augusta University.

Progress in retinal and eye research
|February 12, 2026
PubMed
概括

与年龄相关的白内障 (ARC) 是导致失明的主要原因,由透镜老化驱动. 了解透镜生物学,氧化应激和遗传学是开发新白内障治疗方法的关键.

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相关概念视频

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Proteins perform many mechanical functions in a cell. These proteins can be classified into two general categories- proteins that generate mechanical forces and proteins that are subjected to mechanical forces. Proteins providing mechanical support to the structure of the cell, such as keratin, are subjected to mechanical force, whereas proteins involved in cell movement and transport of molecules across cell membranes, such as an ion pump, are examples of generating mechanical force. 
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Factors Influencing Drug Absorption: Disease States and Pharmacology

Multiple disease states can significantly influence the oral drug absorption process by affecting blood flow and the functionality of the gastrointestinal (GI) system. Various GI diseases, including conditions that alter GI motility, such as diarrhea, decreased acid secretions (achlorhydria), and infections, have been associated with reduced drug absorption.
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Aging01:26

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Aging is a complex biological phenomenon influenced by various processes that affect cellular and systemic functions. Several prominent theories attempt to explain its mechanisms, highlighting cellular limitations, oxidative damage, and hormonal changes as central factors in aging.
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The cellular clock theory posits that the human lifespan is closely tied to the finite capacity of cells to divide, a phenomenon governed by telomeres, which are protective caps at the ends of...
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