老年人多病症和多药性指南的质量和建议:系统性审查
Jiang Yang1, Huiru Li1, Yaolong Chen2
1Collaborative Innovation Center for Chinese Medicine and Respiratory Diseases co-constructed by Henan province & Education Ministry of P.R. China, Zhengzhou, 450000, China.
Ageing research reviews
|February 12, 2026
概括
现有的临床实践指南对于多病症和多药的老年人缺乏严格性和以患者为中心. 未来的指导方针需要改进方法和患者整合,以获得更好的护理.
科学领域:
- 老年学是一门学科.
- 临床实践指南 临床实践指南
- 基于证据的医学基于证据的医学.
背景情况:
- 全球人口老龄化增加了老年人的多病症和多药学挑战.
- 临床实践指南对于管理这些复杂的健康问题至关重要.
- 这一系统审查评估了当前指南的质量,并综合了建议.
研究的目的:
- 评估现有指导方针的方法质量和报告的完整性对老年人多病症/多药性.
- 综合使用Ariadne原则的指导方针建议.
- 为未来的指导方针开发和临床实践提供信息.
主要方法:
- 在2025年8月之前,从九个数据库和五个存储库系统审查指南.
- 包括英语/中文关于老年人多病症或多药性的指南.
- 使用AGREE II,RIGHT,AGREE-REX和GLIA工具进行评估;通过Ariadne原则进行综合.
主要成果:
- 指导方针显示在严格性 (AGREE II:16.7%),报告 (RIGHT:43.2%) 和可执行性 (AGREE-REX:12.5%) 上存在重大缺陷.
- 患者偏好 (42.9%) 和监测 (42.9%) 等关键领域的代表性不足.
- 只有14.3%的指导方针遵守了所有阿里亚德尼原则.
结论:
- 目前针对多病症/多药症老年人的指导方针在方法上很弱,缺乏以患者为中心.
- 建议优先考虑药物安全,而不是整体的纵向护理.
- 未来的指导方针必须加强严格性,整合患者的观点,并专注于个性化护理的实际实施.
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