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Updated: Feb 14, 2026

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突变的NPM1-调节的雌激素信号通过升调HGF促进白血病细胞的生存,并代表了治疗的脆弱性

Jing Yang1, Jun Ren1, Tinglu Tao2

  • 1Department of Oncology, The Beibei Affiliated Hospital of Chongqing Medical University, The Ninth People's Hospital of Chongqing, Key Laboratory of Clinical Laboratory Diagnostics (Chinese Ministry of Education), College of Laboratory Medicine, Chongqing Medical University, Chongqing 400016, China.

Biochemical pharmacology
|February 12, 2026
PubMed
概括

雌激素促进急性髓性白血病 (AML) 的生长,其中NPM1突变,特别是在绝经前妇女中. 向雌激素信号传递为这种具有挑战性的癌症提供了潜在的新疗法.

关键词:
17β-雌二醇是17β-雌二醇中的一种.患有急性髓性白血病的患者.雌激素受体的受体是什么在HGF的基础上.核胺1 的核胺1

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