与MIDLINE导管和外围插入的中央导管相关的静脉血栓栓塞风险,系统性审查和元分析
Davide Santagata1, Francesco Subri1, Chiara Vegliach2
1Medicine and Surgery, University of Insubria, Varese, Italy.
Thrombosis and haemostasis
|February 12, 2026
概括
中线导管 (MCs) 和外围插入的中央导管 (PICCs) 对静脉血栓塞栓症 (VTE) 具有相似的风险. 导管选择不应该仅仅取决于VTE风险,因为两者都有可比的血栓安全概况.
科学领域:
- 血管接入装置 血管接入装置
- 血栓瘤风险评估 血栓瘤风险评估
- 医疗器械安全 医疗器械安全
背景情况:
- 周边插入的中央导管 (PICC) 和中线导管 (MC) 是常见的血管接入.
- 已知与PICCs相关的静脉血栓栓塞 (VTE) 风险,但MCs的血栓安全概况尚不清楚.
- 相互矛盾的证据和各种定义使VTE对MC的风险评估变得复杂.
研究的目的:
- 系统地审查和元分析PICC和MC之间的VTE发病率.
- 为了比较MCs和PICCs的血栓安全概况.
- 根据插入技术,安置设置和出版期来探索VTE率的异质性.
主要方法:
- 系统审查和对比VTE发病率的研究的元分析.
- 主要结局:根据导管类型的VTE发病率 (PICC与MC).
- 为了解决异质性,进行了子组和灵敏度分析.
主要成果:
- 19项研究包括29680个导管 (14,200个MC,15,480个PICC).
- 在MCs (3.5%) 和PICCs (3.8%) (OR=0.92) 之间,总体VTE率没有显著差异.
- 与导管相关的血栓形成率 (CRT) 也没有显著差异 (OR=1.14).
结论:
- 中线导管 (MCs) 呈现出与外围插入的中央导管 (PICCs) 相似的血栓形状.
- 仅仅是VTE风险不足以指导MC和PICC之间的选择.
- 为了最佳的血管接入设备选择,需要进一步的前性研究,使用标准化定义.
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