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Updated: Feb 14, 2026

Precise Phage Mutagenesis with NgTET-Assisted CRISPR-Cas Systems
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Precise Phage Mutagenesis with NgTET-Assisted CRISPR-Cas Systems

Published on: October 14, 2025

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通过基于合成菌体的CRISPR-Cas传递系统有针对性地消除黄金葡萄球菌乳腺炎感染

Nahiara Garmendia-Antoñana1, Pedro Dorado-Morales1,2, Carmen Gil1

  • 1Laboratory of Microbial Pathogenesis, Navarrabiomed-Universidad Pública de Navarra (UPNA)-Hospital Universitario de Navarra (HUN), IdiSNA, Irunlarrea 3, Pamplona, Navarra, Spain.

NPJ biofilms and microbiomes
|February 12, 2026
PubMed
概括

工程化菌群岛 (ePICI) 提供CRISPR-Cas9来杀死金黄色葡萄球菌,为牲畜乳腺炎提供了抗生素的有希望的替代品. 生物膜组成会影响疗效,但ePICI甚至对抗性菌株也表现出有效性.

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