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通过MAPK-CCA1的反调节循环启动了辅酶信号,以刺激酸盐的根源食

Xiaofei Zhang¹, Shanmin Zhou¹, Jingyi Guo²

¹State Key Laboratory of Nutrient Use and Management, College of Resources and Environmental Sciences, National Academy of Agriculture Green Development, China Agricultural University, Beijing, China.

|February 12, 2026

概括

植物MAPK信号调节根生长和酸盐 (NO3-) 的吸收. 这项研究揭示了一个反循环,其中酸盐调节MEKK13/14,激活MAPK级联,最终增强酸盐的根源食.

科学领域:

植物生物学植物生物学
分子信号传输的方法
营养物质感应营养物质感应

背景情况:

线素激活蛋白激酶 (MAPK) 级联对于真核生物的生长和应激反应至关重要.
它们在探测植物营养物质,特别是酸盐 (NO3-) 中的作用尚不清楚.

研究的目的:

研究MAPK信号传递在植物酸盐 (NO3-) 感应和根部发育中的作用.
阐明将酸盐可用性与横向根生长联系起来的监管机制.

主要方法:

对MEKK14中自然发生的突变进行基因分析和精细映射.
对MEKK13/14基因表达的转录分析.
研究涉及NLP7,MKK3,MPK1/2/7/14和CCA1酸化的信号通路.

主要成果:

MEKK14和MEKK13通过促进细胞分裂和扩张来控制横向根延长.
一种特定的MEKK14突变损害了激酶活性,减少了横向根生长和酸盐反应.
酸盐通过NLP7诱导MEKK13/14表达,激活MKK3-MPK1/2/7/14通路.
这种级联酸化和稳定CCA1,创建一个反循环,增强MEKK13/14表达和辅酶介导的酸盐根食.

结论:

MAPK信号传递在植物酸盐 (NO3-) 感应和根源食中起着至关重要的作用.
一个涉及酸化和转录调节的新型积极反循环将酸盐的可用性与根生长和营养获取联系起来.
这项研究扩展了MAPK信号传导在植物营养物质感应中的已知功能.

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