通过Sysmex XT-2000iV和Sysmex XN-1000V在猫的输液中评估的Delta总核细胞的比较
Manuela Zanetti1, Sara Meazzi2,3, Saverio Paltrinieri2
1Antech Diagnostics, Mars Petcare Science & Diagnostics, 20129 Milan, Italy.
Animals : an open access journal from MDPI
|February 13, 2026
概括
来自Sysmex XT-2000iV和XN-1000V分析仪的核细胞计数 (ΔTNC) 的比率在诊断猫出血,包括出血性FIP时显示出可比的准确性. 尽管有一些偏见,但从XT-2000iV的切断线有效地分类了两个平台上的样本.
科学领域:
- 兽医血液学 兽医血液学
- 诊断细胞学 诊断细胞学
- 比较病理学比较病理学
背景情况:
- 来自Sysmex XT-2000iV的核细胞计数比 (ΔTNC) 是用于猫出血分析的经过验证的工具.
- 一个 ΔTNC > 2.5 在诊断流动性猫传染性腹膜炎 (FIP) 中表现出高准确性.
研究的目的:
- 为了比较Sysmex XT-2000iV和Sysmex XN-1000V分析仪之间 ΔTNC测量的诊断实用性.
- 为了评估这些分析器在各种类型的猫液上的性能.
主要方法:
- 通过使用Sysmex XT-2000iV (测量WBC-BASO,WBC-DIFF,DTNC-XT) 和Sysmex XN-1000V (测量TNC-WNR,TNC-WDF,DTNC-XN) 分析了45只猫的输液样本.
- 统计分析包括帕辛和巴布洛克回归和布兰德-阿尔特曼图表,以评估两个分析器的 ΔTNC 值之间的一致性和偏差.
主要成果:
- 两种分析仪在所有评估参数中没有观察到任何显著差异.
- 通过和巴布洛克回归显示了 ΔTNC-XT 与 ΔTNC-XN 的斜率为 1.612 和截止值为 -0.744.
- 发现了正偏差 (4.382),特别是在较高的 ΔTNC 值时,表明分析器之间的比例和恒定偏差.
结论:
- 尽管发现了偏差,但在使用XT-2000iV截止值时,猫液被两种分析仪分类得相似.
- 赛斯美克斯XN-1000V可以与XT-2000iV交替使用,用于猫出血中的ΔTNC分析.
- 这两种分析仪在识别暗示FIP的样本时都保持高准确度.
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