开发和验证低坐高步测试,以评估在肉症下下肢功能
Serpil Demir1, Burak Elçin1, Ramazan Mert1
1Department of Physical Medicine and Rehabilitation, Faculty of Medicine, Akdeniz University, Antalya 07070, Turkey.
Diagnostics (Basel, Switzerland)
|February 13, 2026
概括
低坐高步 (LS-HS) 测试有效评估下肢功能,并检测早期的肉症. 这种可靠和有效的工具有助于监测临床实践中的功能衰退.
科学领域:
- 老年学是一门学科.
- 运动学 运动学
- 生物医学工程 生物医学工程
背景情况:
- 标志着肌肉质量和力量损失的萨尔科佩尼亚,对健康构成重大风险,特别是在老年人中.
- 早期发现肉类是及时干预和管理的关键.
- 现有的评估工具可能缺乏成本效益,临床实用性或早期检测的敏感性.
研究的目的:
- 评估新型低坐高步 (LS-HS) 试验的有效性,可靠性和诊断准确性.
- 评估LS-HS测试在识别早期肉类和功能衰退方面的灵敏度.
- 建立LS-HS测试作为一个成本效益和临床实用的工具,用于下肢评估.
主要方法:
- 一项涉及205名参与者的横截面研究,分为四个组:可能的肉,肉,年轻对照组和中年至老年成人对照组.
- 对LS-HS测试成绩与下肢功能的标准评估进行比较.
- 使用克伦巴赫α和类内相关系数 (ICC) 的可靠性分析.
- 多项逻辑回归和接收器操作特征 (ROC) 曲线分析用于预测能力和诊断准确性.
主要成果:
- 在可能患有和的个体中,LS-HS测试得分显著更高 (p<0.05).
- LS-HS的表现是可能的缩症和缩症 (p<0.001) 的显著预测指标.
- 该测试显示出出色的内部一致性 (克朗巴赫的α=0.938) 和非常高的可靠性 (ICC=0.998).
- 在ROC分析中,对可能的肉病 (AUC = 0.768) 和肉病 (AUC = 0.704) 的诊断准确度很高.
结论:
- LS-HS测试是一种有效,可靠和敏感的下肢功能能力测量方法.
- 它有效地识别了与sarcopenia频谱相关的早期功能衰退.
- LS-HS测试是例行临床评估和肉症监测的实用和有效替代方案.
相关概念视频
Fruit Development, Structure, and Function
25.4K
Fruits form from a mature flower ovary. As seeds develop from the ovules contained within, the ovary wall undergoes a series of complex changes to form fruit. In some fruits, such as soybeans, the ovary wall dries; in other fruits, such as grapes, it remains fleshy. In some cases, organs other than the ovary contribute to fruit formation; such fruits are called accessory fruits.
25.4K
Reliability and Validity
14.1K
Reliability and validity are two important considerations that must be made with any type of data collection. Reliability refers to the ability to consistently produce a given result. In the context of psychological research, this would mean that any instruments or tools used to collect data do so in consistent, reproducible ways.
14.1K
In Vitro Drug Release Testing: Overview, Development and Validation
368
In vitro dissolution and drug release tests assess how quickly and how much of a drug is released from its dosage form into an aqueous medium under standardized laboratory conditions. These tests are essential tools in pharmaceutical development and quality assurance, offering insight into the drug's performance before clinical use.During formulation development, dissolution testing identifies incomplete or inconsistent drug release issues. It also supports decisions on selecting the optimal...
368
Rate-Determining Steps
37.5K
Relating Reaction Mechanisms
In a multistep reaction mechanism, one of the elementary steps progresses significantly slower than the others. This slowest step is called the rate-limiting step (or rate-determining step). A reaction cannot proceed faster than its slowest step, and hence, the rate-determining step limits the overall reaction rate.
The concept of rate-determining step can be understood from the analogy of a 4-lane freeway with a short-stretch of traffic-bottleneck caused due to...
In a multistep reaction mechanism, one of the elementary steps progresses significantly slower than the others. This slowest step is called the rate-limiting step (or rate-determining step). A reaction cannot proceed faster than its slowest step, and hence, the rate-determining step limits the overall reaction rate.
The concept of rate-determining step can be understood from the analogy of a 4-lane freeway with a short-stretch of traffic-bottleneck caused due to...
37.5K
Absolute and Local Extreme Values
87
The highest and lowest values of a function, relative to a reference axis, are known as extreme values. These include absolute maximum and absolute minimum values, which represent the highest and lowest points the function reaches across its entire domain. Within a restricted portion of the function, the highest and lowest values are referred to as local maximum and local minimum values, respectively.Periodic functions, such as sine and cosine, show extreme values at infinitely many points due...
87
Assessment of blood pressure in brachial artery(one-step method)
1.2K
This procedural guide systematically measures blood pressure using an oscillometric digital sphygmomanometer, emphasizing accuracy, patient safety, and comfort.
Prepare for the Procedure:
Prepare for the Procedure:
1.2K


