Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Clinical Trials01:16

Clinical Trials

10.9K
Clinical trials are prospective experimental studies conducted on humans to determine the safety and efficacy of treatments, drugs, diet methods, and medical devices. Using statistics in clinical trials enables researchers to derive reasonable and accurate conclusions from the collected data, allowing them to make wise decisions in uncertain situations. In medical research, statistical methods are crucial for preventing errors and bias.
There are four phases in a clinical trial. A phase one...
10.9K
Clinical Trials: Overview01:11

Clinical Trials: Overview

5.0K
Clinical development focuses on how the drug will interact with the human body and encompasses four key phases of clinical trials, each serving a specific purpose in assessing the safety and effectiveness of new drugs. These phases overlap and build upon one another. Phase I involves a small group of healthy volunteers (typically 20-80 individuals) or, in cases where significant toxicity is expected, patients with the targeted disease, such as cancer or AIDS. The volunteers are tested for...
5.0K
Cancer Prevention02:59

Cancer Prevention

8.2K
Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
8.2K
Statistical Software for Data Analysis and Clinical Trials01:12

Statistical Software for Data Analysis and Clinical Trials

1.6K
Statistical software is pivotal in data analysis and clinical trials by providing tools to analyze data, draw conclusions, and make predictions. These software packages range from simple data management applications to complex analytical platforms, supporting various statistical tests, models, and simulation techniques. Their significance lies in their ability to handle vast amounts of data with precision and efficiency, enabling researchers to validate hypotheses, identify trends, and make...
1.6K
Trial and Error and Algorithm01:12

Trial and Error and Algorithm

430
A problem-solving strategy is a plan of action used to find a solution. Different strategies have distinct action plans. Trial and error involves trying different solutions until one works. For instance, to fix a broken printer, you might check ink levels, ensure the paper tray isn't jammed, and verify the printer's connection to your laptop. This method can be time-consuming but is commonly used. Thomas Edison, for example, used trial and error to find a suitable filament for the light...
430
Prevention of Further Absorption of Poison01:14

Prevention of Further Absorption of Poison

1.3K
In cases of acute poisoning, the primary objective is to prevent further absorption of the toxic substance into the body. Immediate interventions using various decontamination techniques targeting the gastrointestinal (GI) tract can achieve this. Decontamination is crucial to prevent poison from entering the systemic circulation, which involves washing affected areas with water and mild soap and removing contaminated clothing. Once external decontamination is done, attention must be turned to...
1.3K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Mitochondrial DNA breaks and copy number and the risk of lung cancer in the Shanghai Women's Health Study.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology·2026
Same author

Pilot Study of Daily Exemestane in Women with Endometrial Intraepithelial Neoplasia or Low-Grade Endometrial Cancer.

Clinical cancer research : an official journal of the American Association for Cancer Research·2025
Same author

Precision Prevention Studies: A Targeted Approach to Cancer Prevention.

Cancer prevention research (Philadelphia, Pa.)·2025
Same author

Window-of-opportunity trials to screen effective agents and optimize dose in breast cancer prevention.

NPJ breast cancer·2025
Same author

Repurposing Drugs for Cancer Prevention: Targeting Mechanisms Common to Chronic Diseases.

Cancer journal (Sudbury, Mass.)·2024
Same author

A deep-learning framework to predict cancer treatment response from histopathology images through imputed transcriptomics.

Nature cancer·2024

相关实验视频

Updated: Feb 14, 2026

In Silico Clinical Trials for Cardiovascular Disease
09:09

In Silico Clinical Trials for Cardiovascular Disease

Published on: May 27, 2022

2.3K

癌症预防临床试验:进展和挑战

Elizabeth R Francis1, Farzeen Z Syed2, Arun Rajan3

  • 1Thoracic and GI Malignancies Branch, Center for Cancer Research, Cancer Prevention Fellowship Program, Division of Cancer Prevention, Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.

Cancers
|February 13, 2026
PubMed
概括

癌症预防试验在将生物见解转化为公共卫生战略方面面临挑战. 试验方法和免疫预防方面的进步为开发针对多种癌症类型的预防剂提供了新的途径.

关键词:
预防癌症 预防癌症临床试验是指临床试验中的临床试验.作为目标的生殖线致病变体.免疫预防 免疫预防准确预防的准确预防.在早成熟的孕期之前.

更多相关视频

The Use of Pharmacological-challenge fMRI in Pre-clinical Research: Application to the 5-HT System
11:27

The Use of Pharmacological-challenge fMRI in Pre-clinical Research: Application to the 5-HT System

Published on: April 25, 2012

16.0K
Enumeration of Major Peripheral Blood Leukocyte Populations for Multicenter Clinical Trials Using a Whole Blood Phenotyping Assay
14:45

Enumeration of Major Peripheral Blood Leukocyte Populations for Multicenter Clinical Trials Using a Whole Blood Phenotyping Assay

Published on: September 16, 2012

15.5K

相关实验视频

Last Updated: Feb 14, 2026

In Silico Clinical Trials for Cardiovascular Disease
09:09

In Silico Clinical Trials for Cardiovascular Disease

Published on: May 27, 2022

2.3K
The Use of Pharmacological-challenge fMRI in Pre-clinical Research: Application to the 5-HT System
11:27

The Use of Pharmacological-challenge fMRI in Pre-clinical Research: Application to the 5-HT System

Published on: April 25, 2012

16.0K
Enumeration of Major Peripheral Blood Leukocyte Populations for Multicenter Clinical Trials Using a Whole Blood Phenotyping Assay
14:45

Enumeration of Major Peripheral Blood Leukocyte Populations for Multicenter Clinical Trials Using a Whole Blood Phenotyping Assay

Published on: September 16, 2012

15.5K

科学领域:

  • 在瘤学瘤学.
  • 临床试验 临床试验
  • 癌症预防研究 癌症预防研究

背景情况:

  • 预防癌症是减少疾病负担的关键策略.
  • 将早期的致癌性见解转化为公共卫生战略仍然是困难的.
  • 传统的III期试验需要大量人群和长时间的试验.

研究的目的:

  • 审查癌症预防试验的历史和当前状态.
  • 突出发展预防剂的挑战.
  • 讨论最近在试验方法和免疫预防方面的进展.

主要方法:

  • 历史和当前癌症预防试验方法的审查.
  • 讨论生物学和方法学的障碍.
  • 专注于免疫预防策略和试验设计.

主要成果:

  • 早期试验对于改进干预措施和提供安全性/有效性数据至关重要.
  • 最近的进展为该领域带来了活力,为预防多种癌症提供了潜力.
  • 克服固有的障碍是成功开发预防剂的关键.

结论:

  • 癌症预防试验正在随着新方法的发展而发展.
  • 免疫预防为未来的研究提供了有希望的途径.
  • 解决生物和方法上的障碍对于进步至关重要.