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Updated: Feb 14, 2026

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在非小细胞肺癌中LINE-1转录异质性是由宿主基因组背景和保存的功能热点驱动的

Yingshan Wang1, Kenneth S Ramos1

  • 1Center for Genomic and Precision Medicine, Texas A&M Institute of Biosciences and Technology, Houston, TX 77030, USA.

Cancers
|February 13, 2026
PubMed
概括

长间散元素-1 (LINE-1) 逆转移子在肺癌中被重新激活,导致基因组不稳定. 这项研究描述了非小细胞肺癌细胞系中的LINE-1活性,揭示了保存模式和潜在的瘤原因相互作用.

关键词:
线路-1 线路-1 在线功能性热点是指功能性热点.不同质性的异质性非小细胞肺癌的肺癌.

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