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Updated: Feb 14, 2026

Establishment of a Human Multiple Myeloma Xenograft Model in the Chicken to Study Tumor Growth, Invasion and Angiogenesis
10:04

Establishment of a Human Multiple Myeloma Xenograft Model in the Chicken to Study Tumor Growth, Invasion and Angiogenesis

Published on: May 1, 2015

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在多发性骨髓瘤患者中,蛋白质酶抑制剂相关心脏毒性的表观基因组广泛关联研究

Raed Awadh Alshammari1,2, Samuel M Rubinstein3, Eric Farber-Eger4

  • 1Department of Pharmacotherapy and Translational Research and Center for Pharmacogenomics and Precision Medicine, College of Pharmacy, University of Florida, Gainesville, FL 32610-0486, USA.

Cancers
|February 13, 2026
PubMed
概括

这项研究在多发性骨髓瘤患者中发现了与心血管不良事件 (CVAE) 相关的明显的DNA甲基化变化,这些患者接受了卡菲尔佐米布或博特佐米布治疗,这表明表观遗传因素有助于这些副作用.

关键词:
通过DNA甲基化.欧洲经济联盟 (EWAS) 的成员.博尔特佐米布 (Bortezomib) 是一种药物.心脏瘤学心脏瘤学卡菲尔佐米比 (Carfilzomib) 是一种药物.这是表观遗传学.

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