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Polymers02:34

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The word polymer is derived from the Greek words “poly” which means “many” and “mer” which means “parts”. Polymers are long chains of molecules composed of repeating units of smaller molecules, known as monomers. They either occur naturally, such as DNA and proteins, or can be constructed synthetically, like plastics. They have varied structural characteristics, such as linear chains, branched chains, or complex networks, that contribute to the...
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In statistics, several tools are used to interpret the data. Measures of central tendency represent the characteristics of the data, such as mean, median, and mode. Additionally, measures of variance like standard deviation and range are used to find the spread of data from the mean. Relative standing measures the distance between data locations. Commonly used measures of relative standings are percentile, z score, and quartiles.
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Data are individual items of information obtained from a population or sample. Data may be classified as qualitative (categorical), quantitative continuous, or quantitative discrete. Because it is not practical to measure the entire population in a study, researchers use samples to represent the population. A random sample is a representative group from the population chosen by using a method that gives each individual in the population an equal chance of being included in the sample. Random...
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Matter: Pure Substances and Mixtures
According to its composition, the matter can be classified into two broad categories — pure substances and mixtures. 
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Scientists always try their best to record measurements with the utmost accuracy and precision. However, sometimes errors do occur. These errors can be random or systematic. Random errors are observed due to the inconsistency or fluctuation in the measurement process, or variations in the quantity itself that is being measured. Such errors fluctuate from being greater than or less than the true value in repeated measurements. Consider a scientist measuring the length of an earthworm using a...
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用于3D打印骨植入物的生物活性聚合物复合材料:系统性审查

Anastassiya Khrustaleva1, Dmitriy Khrustalev1, Azamat Yedrissov1

  • 1School of Pharmacy, Karaganda Medical University, Gogol Street 40, Karaganda 100008, Kazakhstan.

Polymers
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概括

用于骨架的生物活性聚合物复合物显示出希望,但缺乏多功能性和体内验证. 未来的研究应该专注于将抗菌剂和生物活性分子纳入增强再生医学应用中.

关键词:
通过3D打印打印3D打印.添加剂制造 添加剂制造 添加剂制造生物活性复合物 生物活性复合物生物活性聚合物的生物活性聚合物.骨组织工程 骨组织工程

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科学领域:

  • 再生医学是一种再生医学.
  • 生物材料科学 生物材料科学
  • 材料工程 材料工程 材料工程

背景情况:

  • 基于聚合物的生物活性复合物对再生医学至关重要.
  • 合成热塑性聚合物如聚乳酸 (PLA) 和聚烯酸 (PCL) 广泛用于承载性骨架.
  • 目前的研究经常使用酸 (HA) 或生物活性玻璃 (BG) 进行骨质导电.

研究的目的:

  • 确定用于骨组织工程的生物活性聚合物复合材料的趋势和知识差距.
  • 检查负载支架的材料设计的翻译相关性.
  • 专注于合成热塑性聚合物和增材制造.

主要方法:

  • 546个出版物的图书统计和内容分析 (2016-2025年).
  • 对106项相关研究进行选和选择.
  • 对生物活性复合材料的研究轨迹的分析.

主要成果:

  • 大多数研究使用PLA或PCL复合材料与HA或BG,实现骨质导电性但有限的多功能性.
  • 抗菌剂,离子释放成分和天然生物活性分子的代表性不足.
  • 不到20%的研究包括体内验证,这表明需要更多的临床前研究.

结论:

  • 为了增强具有多功能性的生物活性聚合物复合材料,存在显著的空间.
  • 未来的研究应该优先考虑纳入各种生物活性剂,并增加体内验证.
  • 需要一个结构化的框架来设计下一代骨组织工程材料.