在父母或兄弟姐妹死于癌症后,年轻人的长期悲伤相关症状:系统性审查和元分析
Chen Ee Low1, Jia Yang Tan1, Weiling Amanda Tan2
1Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119228, Singapore.
Journal of clinical medicine
|February 13, 2026
概括
经历父母或兄弟姐妹癌症损失的年轻人往往会出现长期的悲伤症状,近一半的人报告了症状. 兄弟姐妹的丧失表明,这些持续的悲伤症状的患病率更高.
科学领域:
- 心理学 心理学 心理学
- 在瘤学瘤学.
- 悲伤研究 悲伤研究
背景情况:
- 童年,青少年和年轻人的丧亲可能会导致各种各样的悲伤反应.
- 一大批丧失亲人的人会经历持续或严重的悲伤症状.
- 了解长期悲伤的患病率和风险因素对于支持性护理至关重要.
研究的目的:
- 在父母或兄弟姐妹癌症死亡后,系统地审查和元分析年轻人 (≤25岁) 长期悲伤症状的患病率和预后因素.
- 确定与长期悲伤相关症状风险增加相关的因素.
主要方法:
- 在PubMed,MedLine,Embase和PsycINFO的系统文献搜索.
- 包括13项关于长期悲伤症状 (损失后≥6个月) 的研究 (5项用于元分析).
- 随机效应对流行率的元分析;对预后因素的横截面研究.
主要成果:
- 自我报告的长期悲伤症状的综合流行率为48% (95%CI:29-67%).
- 患病率是28% (95% CI: 7-65%) 失去父母后和59% (95% CI: 45-72%) 失去兄弟姐妹后.
- 以前存在的抑郁症,情绪困难和失眠与症状升高有关.
结论:
- 长期的悲伤症状在因父母或兄弟姐妹的癌症损失而丧生的年轻人中很常见,特别是兄弟姐妹的损失.
- 研究措施的大量异质性限制了解释;长期悲伤障碍的正式诊断是不可能的.
- 需要使用经过验证的仪器进行进一步的严格研究,以指导对失去年轻人的干预.
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