在试管婴儿后预测活产的临床适用诺莫图:Zubeyde Hanim模型
Pınar Karaçin1, Runa Özelçi2, Enes Kumcu2
1Department of Gynecology, Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital, Ankara 06200, Türkiye.
Journal of clinical medicine
|February 13, 2026
概括
这项研究开发了Zübeyde Hanim IVF Nomogram,用于预测体外受精 (IVF) 后的活产. 诺米图使用常规临床数据来帮助咨询患者并有效规划试管婴儿治疗.
科学领域:
- 生殖医学 生殖医学
- 在体外受精 (IVF)
- 临床预测模型临床预测模型
背景情况:
- 在试管婴儿中预测活产对于患者咨询和治疗计划至关重要.
- 现有的预测模型可能无法有效利用常规可用的临床和胚胎学数据.
研究的目的:
- 开发和验证一种临床上适用的诺米克图,用于预测试管婴儿后的活产.
- 用例行收集的数据确定活产的关键预测因素.
主要方法:
- 在一个单一的三级试管婴儿中心进行了回顾性研究.
- 包括2119个IVF/ICSI周期与胚胎移植和已知的活产结果.
- 多变量后勤回归分析以确定活产的独立预测因素.
主要成果:
- 祖贝德·汉尼姆试管婴儿输卵表 (Zübeyde Hanim IVF Nomogram) 是使用女性年龄,胚胎质量,胚胎移植日和子宫内膜厚度来开发的.
- 该名录显示可接受的区分 (AUC:0.64) 和令人满意的校准.
- 确定了关键预测因素:女性年龄 (OR:0.959),高胚胎质量 (OR:2.752),第5天移植 (OR:1.427) 和子宫内膜厚度 (OR:1.086).
结论:
- 祖贝德·哈尼姆试管婴儿视图 (Zübeyde Hanim IVF Nomogram) 是个性化预测试管婴儿活产的实用工具.
- 诺米图帮助临床医生为患者提供咨询,并优化治疗策略.
- 使用常规可用的参数,以提高临床适用性.
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