患有间歇性肺部疾病的患者的神经症状频率,认知功能障碍和运动障碍:横截面分析
Zsolt Vastag1,2,3, Emanuela Tudorache1,4, Daniel Traila1,4
1Center for Research and Innovation in Personalised Medicine of Respiratory Diseases (CRIPMRD), Pulmonology University Clinic, "Victor Babes" University of Medicine and Pharmacy, 300041 Timisoara, Romania.
Journal of clinical medicine
|February 13, 2026
概括
间歇性肺部疾病 (ILD) 与更多的神经症状和认知问题有关. 早期识别和综合护理对于管理这些复杂的患者需求至关重要.
科学领域:
- 肺部病理学 肺部病理学
- 神经学 神经学
- 临床医学 临床医学
背景情况:
- 间歇性肺部疾病 (ILD) 越来越多地与神经问题有关,如认知能力下降和运动缺陷.
- 在ILD患者中,这些神经症状的患病率和严重程度需要进一步调查.
研究的目的:
- 在ILD和非ILD患者之间比较神经症状和功能.
- 使用标准化测试评估认知和运动性能.
- 确定神经系统参与ILD的风险因素.
主要方法:
- 77名患者 (40名ILD,37名非ILD) 的截面研究.
- 评估了神经症状,认知功能 (MoCA,SDMT) 和运动功能 (BBS,TUG,SLS,GPT).
- 收集人口统计数据,吸烟情况和BMI.
主要成果:
- 在ILD患者中,神经症状 (42.5%与16.2%) 和震 (35%与11%) 的患病率较高.
- 在ILD患者中观察到下单腿姿势 (SLS) 评分 (p=0.03).
- 在ILD患者中,蒙特利尔认知评估 (MoCA) 评分较低的情况更为频繁 (<26,45%,19%).
结论:
- ILD与增加的神经症状和微妙的认知/运动障碍有关.
- 诊断ILD,年龄较大和吸烟史是神经系统参与的独立风险因素.
- 综合,多学科的方法对于管理ILD患者的神经表现至关重要.
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