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桃体切除术,桃体切除术,腺体切除术或桃体切除术后的常规组织组织制备:在资源紧缩的时代,一个必要的诊断?
Givi Magradze1, Felix Deffner1, Manuel Christoph Ketterer1
1Department of Otorhinolaryngology, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany.
Journal of clinical medicine
|February 13, 2026
概括
在桃切除术,桃切除术,腺切除术或切除术 (TTAC) 后的例行组织学检查很少产生重大发现. 这项研究表明是这样的.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 病理学 病理学 病理学
- 手术瘤学手术瘤学
背景情况:
- 常规组织学检查桃体切除术,桃体切除术,腺体切除术或桃体切除术 (TTAC) 的组织是常见的做法.
- 在没有特定风险因素的患者中,例行组织学检查的临床效用和成本效益受到辩论.
- 经过TTAC后需要治疗的意外发现很少见,需要评估当前的诊断方案.
研究的目的:
- 为了确定在TTAC标本的例行组织学检查后需要治疗的意外发现的流行率.
- 在没有明显风险因素的患者中评估例行组织学检查的价值.
- 通过完善组织学检查协议来评估降低成本和资源利用的潜力.
主要方法:
- 在2011年至2021年期间,对5709名在TTAC后接受例行组织学检查的患者进行了回顾性研究.
- 数据收集包括患者的人口统计,手术细节,手术指示,组织检查和组织学结果.
- 分析的重点是确定异常发现和随后治疗的需要.
主要成果:
- 在5709个TTAC标本中,只发现了4个异常组织学发现 (0.07%).
- 在四个异常发现中,有三个是在成年患者身上发现的,包括粒状炎症,伯基特淋巴瘤和慢性淋巴细胞白血病/小细胞B淋巴瘤.
- 在排除了非新发性疾病并对一个病例采用了观察和等待策略后,只有一个患者 (0.0175%) 需要治疗.
结论:
- 在TTAC之后的例行组织学检查对于没有特定风险因素 (例如吸烟,无法解释的疼痛,可疑的病变) 的患者是不有益的.
- 显著发现的低患病率表明,例行组织学检查可能会导致不必要的成本和资源利用.
- 组织学检查应保留在临床或历史记录怀疑恶性瘤的情况下.
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