结核病暴露频率和潜伏结核病感染率在医疗保健工作者中的比较,按职业分类.
Seran Cheon1, Si-Ho Kim1,2, Ji Hong Park1
1Center for Infection Prevention and Control, Samsung Changwon Hospital, Changwon 51353, Republic of Korea.
Journal of clinical medicine
|February 13, 2026
概括
卫生保健工作者分类有效预测结核病暴露频率. 然而,潜伏结核病感染的发病率与多次暴露事件有关,而不是工作风险组.
科学领域:
- 职业健康 职业健康 职业健康
- 传染病流行病学 传染病流行病学
- 公共卫生政策 公共卫生政策
背景情况:
- 韩国疾病控制和预防局将医疗保健工作者分为五个结核病 (TB) 查风险组.
- 在这些HCW分类中,关于实际结核病暴露频率和潜在结核病感染 (LTBI) 发生率的数据有限.
- 这项研究解决了基于风险分层的HCW之间了解结核病暴露和LTBI发展的差距.
研究的目的:
- 评估HCW职业分类与结核病暴露频率之间的相关性.
- 为了确定高压工人中LTBI的发病率.
- 评估LTBI发病率和职业风险群体与结核病暴露事件数量之间的关联.
主要方法:
- 一项回顾性队列研究,涉及2023-2024年在第三级医院的2116名HCW.
- 基线和年度LTBI查1-4组的HCW,记录了结核病暴露史.
- 对初始查结果为负的HCW计算的LTBI发病率,后者进行了重复测试.
主要成果:
- 每人结核病暴露率和平均暴露事件在风险分类较高时显著增加 (p < 0.001).
- 整体LTBI发生率为1.0% (13/1323个HCW).
- 长期性结核病发病率与两个或两个以上的结核病暴露事件 (aOR,7.03;p = 0.005) 有显著的关联,但与职业组分类没有关联.
结论:
- 职业分类有效地预测了HCW中结核病暴露频率.
- 在HCW中,LTBI的发病率与结核病暴露事件的数量比与其分配的风险分类更强烈相关.
- 研究结果表明,需要考虑结核病预防策略中的累积暴露.
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