在缺血性心脏病的整个谱的冠状动脉生理学
Ciro Pollio Benvenuto1,2, Luigi Cappannoli3, Andrea Viceré1
1Department of Cardiovascular Science, Università Cattolica del Sacro Cuore, Largo Agostino Gemelli 8, 00168 Rome, Italy.
Journal of clinical medicine
|February 13, 2026
概括
冠状动脉综合征带来了重大的心血管风险. 本综述探讨了用于诊断缺血,指导治疗和改善急性冠状动脉综合征 (ACS) 和慢性冠状动脉综合征 (CCS) 的预后的侵入性功能评估.
科学领域:
- 心脏病学 心脏病学
- 心血管医学 心血管医学
- 干预心脏病学 干预心脏病学
背景情况:
- 急性和慢性冠状动脉综合征 (ACS/CCS) 是导致心血管死亡的主要原因.
- 这些综合症涉及到表心和微血管冠状动脉区的复杂结构和功能异常.
- 为了研究冠状动脉疾病的全谱,必须采取全面的方法.
研究的目的:
- 审查冠状动脉生理学的当前证据.
- 讨论侵入性功能评估在临床实践中的最佳应用.
- 解决ACS和CCS功能评估的不足和异质性问题.
主要方法:
- 关于冠状动脉疾病侵袭性功能评估现有文献的综述.
- 分析功能评估技术的演变,从指导复血管化到表征缺血.
- 讨论缺血症表征和预后分层的协议.
主要成果:
- 侵入性功能评估已经发展成为一种细致的协议,用于表征缺血和分层预后.
- 尽管有好处,但冠状动脉生理在临床实践中未得到充分利用.
- 在不同中心的功能评估方案中存在显著的异质性.
结论:
- 对冠状动脉生理学的全面理解和标准化应用对于管理ACS和CCS至关重要.
- 需要进一步的研究和共识,以优化功能评估在常规临床实践中的使用.
- 在诊断和管理冠状动脉综合征时利用冠状动脉生理学的最佳实践需要进一步阐明.
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