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树脂入剂在非化闭塞性病变中的有效性:系统性审查
Samille Biasi Miranda1, Rodrigo Barros Esteves Lins2, Julia Almeida Maciel da Silveira1
1Department of Dental Materials, Faculty of Dentistry, University of Pernambuco, Recife 50100-130, PE, Brazil.
Journal of clinical medicine
|February 13, 2026
概括
树脂透剂 (RI) 在管理非化闭膜病变 (NCOCLs) 中表现有前途,其有效性与密封剂相当. 然而,需要更多的长期临床研究来确认它们的耐用性和持续有效性.
科学领域:
- 牙损管理 牙损管理
- 最少侵入性牙科是最少侵入性的牙科.
背景情况:
- 非化闭口病变 (NCOCLs) 代表了牙的早期阶段.
- 树脂透剂 (RI) 提供一种最少的侵入性方法来阻止病变的进展.
研究的目的:
- 系统地审查树脂透剂 (RIs) 在控制初级和永久牙中NCOCLs的有效性.
- 为了比较RI疗效与安慰剂和其他牙科材料.
主要方法:
- 在遵守PRISMA指南的基础上进行系统审查.
- 包括随机临床试验 (RCT) 和体外/体外研究.
- 在五个数据库和灰色文献中搜索到2025年12月.
- 使用RoB 2.0和GRADE工具评估的偏见风险和证据确定性.
主要成果:
- 包括八项研究:两项RCT和六项体外/体外实验.
- 试验证据表明,与RIs相比,可与传统密封剂相比,可减少虫病的进展.
- 试验室研究显示,通过优化协议,树脂透和密封性得到改善.
- 偏差风险低至中等;临床证据的确定性低.
结论:
- 树脂透剂 (RI) 可以有效地管理NCOCL,与传统的预防方法相似.
- 有限的RCT和短的随访期削弱了当前的证据基础.
- 进一步的长期临床研究对于验证RI的持续有效性和耐用性至关重要.
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