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功能性食品的进步:使用双乳液凝来提供CBD和益生菌,并调节人类肠道微生物群落
Sigita Jeznienė1, Ina Jasutienė1, Milda Keršienė1
1Department of Food Science and Technology, Faculty of Chemical Technology, Kaunas University of Technology, Radvilėnų Av. 19, LT-50254 Kaunas, Lithuania.
Nutrients
|February 13, 2026
概括
一种新型的双乳液凝有效地提供了大麻素 (CBD) 和益生菌Lactiplantibacillus plantarum. 这种功能性食品创新调节了肠道微生物群,增强了有益的代谢物,显示了肠道健康的潜力.
科学领域:
- 胃肠道学和微生物学
- 药物输送系统 药物输送系统
- 功能性食品 功能性食品
背景情况:
- 研究新型的输送系统,用于同时服用大麻素 (CBD) 和益生菌.
- 评估双乳液凝的有效性,用于封装DSM 24624和CBD.
研究的目的:
- 评估CBD和L.L.的输送,释放和持久性. 脚部使用双重乳液凝.
- 分析CBD-益生菌配方对肠道微生物组成,多样性和代谢活性的影响.
主要方法:
- 在六周的时间里,利用了动态模拟器人类肠道微生物生态系统 (SHIME®) 模型.
- 采用16S rRNA基因测序和数字PCR进行微生物分析.
- 监测微生物的变化,多样性和代谢物 (丁酸盐,乳酸盐) 的产生.
主要成果:
- 显著调节粘膜和光线微生物群,增加了Lachnospiraceae和Clostridiaceae.
- 证明了成功的分娩,释放和持续的L. 脚 (plantarum) 是指脚下的一个部分.
- 观察到增强了有益代谢物的产生,如丁酸盐和乳酸盐.
结论:
- 双乳液凝是一种可行的系统,可以将益生菌和CBD输送到胃肠道.
- CBD-益生菌配方显示出作为一种功能性食物的潜力,通过调节微生物群来改善肠道健康.
- 需要进一步的体内和临床研究来验证这些体外发现.
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