肠道微生物群对人类认知功能的影响
Soghra Bagheri1, Ireneusz Ryszkiel2, Agata Stanek2
1Medical Biology Research Center, Health Technology Institute, Kermanshah University of Medical Sciences, Kermanshah 6714415185, Iran.
Nutrients
|February 13, 2026
概括
人的肠道微生物群对健康和疾病的认知功能产生影响. 最近的人类研究表明潜在的因果关系,尽管肠道细菌和大脑功能之间的确切关系是复杂的,仍在调查中.
科学领域:
- 神经科学是一个神经科学.
- 微生物学 微生物学
- 人类健康 人类健康 人类健康
背景情况:
- 肠道微生物组在生理和病理功能中的作用是越来越多的研究领域.
- 认知功能是人类健康的一个关键方面,受到各种生物因素的重大影响.
- 现有的研究严重依赖于动物模型,限制了对人类认知过程的直接适用性.
研究的目的:
- 综合了最近关于肠道微生物组和认知功能的人类研究.
- 为了解决动物模型在这个领域的概括性的局限性.
- 提供与认知有关的人类肠-大脑轴的最新概述.
主要方法:
- 对最近的人类研究进行系统审查.
- 干预和观察研究的分析.
- 综合发现,将肠道微生物群组成与认知表现联系起来.
主要成果:
- 肠道微生物群与健康个体和患有疾病的人的认知功能有显著的关联.
- 有证据表明,肠道微生物组成和认知能力之间存在潜在的因果关系.
- 一些研究表明存在相反的关系,强调了肠-大脑轴的复杂性.
结论:
- 人的肠道微生物组在调节认知功能方面发挥着至关重要的作用.
- 需要进一步以人为中心的研究来阐明肠-大脑连接背后的机制.
- 了解这种关系可能会导致针对认知障碍的新型治疗策略.
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