年轻成年人的酒精消费模式和外围动脉硬:来自EVA-Adic研究的性别特定发现
Alberto Vicente-Prieto1,2, Cristina Lugones-Sánchez1,2,3, Sara Vicente-Gabriel1,2,4
1Primary Care Research Unit of Salamanca (APISAL), Salamanca Primary Care Management, Institute of Biomedical Research of Salamanca (IBSAL), 37005 Salamanca, Spain.
Nutrients
|February 13, 2026
概括
酒精消费与年轻成年人的外围动脉硬有关,观察到不同的性别特异性模式. 这些发现强调了在早期的血管衰老评估中考虑性别和血管区域的重要性.
科学领域:
- 心血管健康 心血管健康
- 血管生理学 血管生理学
- 公共卫生 公共卫生
背景情况:
- 关于酒精摄入量与血管功能之间的联系仍在争论中.
- 动脉硬是心血管风险的早期指标.
- 了解年轻人的早期血管变化对于长期健康至关重要.
研究的目的:
- 调查西班牙年轻成年人的酒精消费 (总和饮料类型) 与动脉硬之间的联系.
- 探索酒精对血管功能的性别特异性模式.
- 为了评估不同血管区域的动脉硬度.
主要方法:
- 在西班牙萨拉曼卡对501名年轻成年人 (18-34岁) 的横截面研究.
- 酒精摄入量通过问卷量化 (每周克,按类型).
- 动脉硬度用脉冲压力 (PP),大脑椎脉冲波速率 (cf-PWV),臂脚脉冲波速率 (ba-PWV),心脚血管指数 (CAVI) 和中央增强指数 (CAIx75) 来测量.
主要成果:
- 酒精消费者比禁酒者表现出较低的脚脉冲波速度 (ba-PWV).
- 在男性中,较高的总酒精,酒和烈酒摄入量与较低的ba-PWV相关.
- 在女性中,酒精消费与中央增强指数与每分钟75次心率 (CAIx75) 校正的心率有关.
结论:
- 酒精消费与年轻成年人的外围动脉硬 (ba-PWV) 有关,性别差异显著.
- 由于研究设计,研究结果建议谨慎解释;不暗示因果关系.
- 强调在评估早期血管衰老时需要考虑性别和血管区域.
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