纯母乳养并不能确保在出生时体重非常低的早产婴儿中获得足够的维生素B状态
Anne-Lise Bjørke-Monsen1,2, Ingrid Kristin Torsvik2, Mariann Haavik Lysfjord Bentsen2
1Laboratory of Medical Biochemistry, Førde Hospital Trust, 6807 Førde, Norway.
Nutrients
|February 13, 2026
概括
对于早产VLBW婴儿,纯母乳养可能无法提供足够的B族维生素. 补充和定期监测对于婴儿的最佳发育和生长至关重要.
科学领域:
- 儿童营养学 儿童营养学
- 微量营养素的新陈代谢
- 新生儿健康 新生儿健康
背景情况:
- 建议对早产VLBW婴儿进行纯母乳养.
- 维生素B对婴儿发育至关重要,包括DNA甲基化.
- 这项研究评估了VLBW婴儿母乳养与配方奶粉的B族维生素状况.
研究的目的:
- 为了比较VLBW婴儿的B族维生素状态 (可巴胺,叶酸,B6,B2) 在纯母乳和配方奶粉中.
- 为了评估母乳养中B族维生素摄入量在前6个月的适当性,调整年龄.
- 确定潜在的缺陷,并为VLBW婴儿提供营养建议.
主要方法:
- 在VLBW婴儿中测量了维生素B12,叶酸,B6 (PLP),B2水平和代谢标志物 (tHcy,MMA).
- 婴儿在预产期,2个月,6个月和12个月被评估,年龄修正.
- 纯母乳养和配方奶粉养的VLBW婴儿之间的营养状况比较.
主要成果:
- 与配方奶粉养的婴儿相比,纯母乳养的婴儿的可巴拉明,PLP和利博水平较低.
- 80%的仅母乳养的婴儿在前6个月内表现出可巴胺缺乏症 (tHcy ≥6.5μmol/L) 的迹象.
- 3-9%的婴儿表现出一种或多种维生素B的缺乏,更常见的是母乳养的婴儿.
结论:
- 只有纯母乳养,没有适当的多维生素补充,不能确保VLBW婴儿的足够的B维生素状态.
- 目前对VLBW婴儿的营养建议需要改善微量营养素摄入量.
- 对维生素状况的定期监测对于早产VLBW婴儿的随访护理至关重要.
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