Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Levels of Organization01:09

Levels of Organization

141.7K
Biological organization is the classification of biological structures, ranging from atoms at the bottom of the hierarchy to the Earth's biosphere. Each level of the hierarchy represents an increase in complexity that builds upon the previous level.
Molecules Are Composed of Atoms, and Biomolecules Are Assembled from Molecules:
The most basic levels include atoms, molecules, and biomolecules. Atoms, the smallest unit of ordinary matter, are composed of a nucleus and electrons. Molecules...
141.7K
Accessory Organs01:31

Accessory Organs

74.5K
Accessory organs are those that participate in the digestion of food but do not come into direct contact with it like the mouth, stomach, or intestine do. Accessory organs secrete enzymes into the digestive tract to facilitate the breakdown of food.
74.5K
Organic Compounds03:02

Organic Compounds

57.7K
All living things are formed mostly of carbon compounds called organic compounds. The category of organic compounds includes both natural and synthetic compounds that contain carbon. Although a single, precise definition has yet to be identified by the chemistry community, most agree that a defining trait of organic molecules is the presence of carbon as the principal element, bonded to hydrogen and other carbon atoms. However, some carbon-containing compounds such as carbonates, cyanides, and...
57.7K
Transgenic Organisms00:53

Transgenic Organisms

33.7K
Overview
33.7K
Chromatin Immunoprecipitation- ChIP02:36

Chromatin Immunoprecipitation- ChIP

12.5K
Chromatin immunoprecipitation, or ChIP, is an antibody-based technique used to identify sites on DNA that bind to transcription factors of interest or histone proteins. It also helps determine the type of histone modifications such as acetylation, phosphorylation, or methylation.
Types of ChIP
ChIP can be divided into two types - X-ChIP and N-ChIP. X-ChIP involves in vivo cross-linking of histones and regulatory proteins to DNA, fragmenting the DNA by sonication, and isolating the protein-DNA...
12.5K
Organization of Genes02:07

Organization of Genes

73.7K
Overview
73.7K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Infill Pattern-Dependent Mechanical Properties and In Vitro Release Behavior of FDM 3D-Printed Resveratrol Amorphous Solid Dispersion Matrix Tablets.

Polymers·2026
Same author

MXene-Based Piezoelectric and Triboelectric Energy Harvesters for Personalized Monitoring and Therapeutics.

Small (Weinheim an der Bergstrasse, Germany)·2026
Same author

[Exploration of the value of VAS score in the diagnosis and treatment of patients with vestibular diseases during caloric test].

Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery·2026
Same author

Tongue Image Analysis and Clinical Data Fusion: A Novel Approach for Non-invasive Diagnosis of Metabolic Dysfunction-associated Fatty Liver Disease.

Journal of clinical and translational hepatology·2026
Same author

Anaerobic transformation of 6PPD-Q in sediment: Dominated by quinone reduction and novel O-methylation pathways.

Environmental pollution (Barking, Essex : 1987)·2026
Same author

Autophagy-Enhanced Nanoplatforms Eliminate Intracellular Bacteria and Block Bacteria-Driven Epithelial-Mesenchymal Transition for Tumor Metastasis Inhibition.

ACS nano·2026

相关实验视频

Updated: Feb 14, 2026

Fabrication and Validation of an Organ-on-chip System with Integrated Electrodes to Directly Quantify Transendothelial Electrical Resistance
10:51

Fabrication and Validation of an Organ-on-chip System with Integrated Electrodes to Directly Quantify Transendothelial Electrical Resistance

Published on: September 26, 2017

17.1K

机械器官在芯片上用于癌症研究

Luyang Wang1,2, James Chung Wai Cheung3, Xia Zhao1,2

  • 1School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, China.

International journal of molecular sciences
|February 13, 2026
PubMed
概括

机械器官芯片 (Mechano-OoC) 平台集成机械线索来建模瘤微环境,推进癌症研究. 这些系统提供了一个与人类相关的方法,用于开发精确癌症治疗的预测性临床前模型.

关键词:
在芯片上的机械器官.机械传导 机械传导微生理系统的微生理系统瘤微环境机制 瘤微环境机制

更多相关视频

Easy and Accurate Mechano-profiling on Micropost Arrays
10:25

Easy and Accurate Mechano-profiling on Micropost Arrays

Published on: November 17, 2015

11.6K
Scalable Fabrication of Stretchable, Dual Channel, Microfluidic Organ Chips
14:44

Scalable Fabrication of Stretchable, Dual Channel, Microfluidic Organ Chips

Published on: October 20, 2018

27.6K

相关实验视频

Last Updated: Feb 14, 2026

Fabrication and Validation of an Organ-on-chip System with Integrated Electrodes to Directly Quantify Transendothelial Electrical Resistance
10:51

Fabrication and Validation of an Organ-on-chip System with Integrated Electrodes to Directly Quantify Transendothelial Electrical Resistance

Published on: September 26, 2017

17.1K
Easy and Accurate Mechano-profiling on Micropost Arrays
10:25

Easy and Accurate Mechano-profiling on Micropost Arrays

Published on: November 17, 2015

11.6K
Scalable Fabrication of Stretchable, Dual Channel, Microfluidic Organ Chips
14:44

Scalable Fabrication of Stretchable, Dual Channel, Microfluidic Organ Chips

Published on: October 20, 2018

27.6K

科学领域:

  • 生物物理学的生物物理.
  • 癌症生物学 癌症生物学
  • 微流体学 微流体学

背景情况:

  • 机械因素极大地调节了癌症的进展,转移和治疗反应.
  • 传统的体外模型很难捕捉瘤微环境的生物物理复杂性.
  • 机械生物学和瘤芯片研究通常被单独研究.

研究的目的:

  • 审查用于癌症研究的机器器官芯片 (Mechano-OoC) 技术的进展.
  • 突出将工程机械线索与微流体和其他接口集成的战略.
  • 讨论新出现的读数,数据分析和翻译的挑战.

主要方法:

  • 工程机械线索与微流体学的整合.
  • 使用可调节的细胞外矩阵,血管/流体接口和动态负载.
  • 开发传感器集成平台和人工智能辅助的数据分析.

主要成果:

  • 机械OoC平台可以模拟瘤入侵,血管运输,免疫贩运和药物输送.
  • 新兴的方法有助于实时,多式联运读取.
  • 人工智能辅助的分析增强了数据的解释.

结论:

  • 机械-OoC平台为机械生物学意识的瘤模型提供了一个统一的框架.
  • 这些平台指导了用于精确癌症治疗的预测性临床前模型的开发.
  • 解决设备复杂性,标准化和验证方面的挑战对于翻译至关重要.