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Updated: Feb 14, 2026

High Throughput Sequential ELISA for Validation of Biomarkers of Acute Graft-Versus-Host Disease
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在患有急性移植与宿主疾病的儿科患者中,基于模型的阿巴cept剂量建议

Rui Zhong1,2, Kelly Maxwell3, Julie Passarell3

  • 1Division of Pharmacotherapy and Experimental Therapeutics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.

Journal of clinical pharmacology
|February 13, 2026
PubMed
概括

这项研究建议为2至6岁的儿科患者服用15毫克/千克的加载剂量,然后为12毫克/千克的维持剂量服用阿巴切,这些患者接受了血液生成干细胞移植,以预防急性移植对宿主疾病 (aGVHD). 这种方案确保了安全和有效的阿巴cept暴露.

关键词:
这就是 abataceptcept.接种对宿主病的疾病.儿科的剂量选择.人口的药理动力学

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