无模板的微流体制造水在水中微囊的控制释放
Mingjie Li1, Xiaotong Song1, Joseph D Berry1
1Department of Chemical Engineering, University of Melbourne, Parkville, Victoria 3010, Australia.
ACS applied materials & interfaces
|February 13, 2026
概括
这项研究提出了一种新的微流体方法,用于在单一水相中创建水在水中的微囊. 这种无模板的方法使用受控的协,以在水性配方中制造稳定,尺寸选择性的微囊.
科学领域:
- 材料科学 材料科学 材料科学
- 化学工程是化学工程的重要组成部分.
- 生物技术是生物技术.
背景情况:
- 在完全可混合的水性单相系统 (AOPS) 中制造微囊是具有挑战性的,因为缺乏明显的接口.
- 传统方法依赖于不可混合的系统,如油水或水性双相系统 (ATPS),限制了应用.
研究的目的:
- 开发一种无模板的微流体策略,用于在单个完全可混合的水相中形成微囊.
- 克服现有的微囊制造技术的局限性.
主要方法:
- 使用微流体装置控制相反电荷的聚合物和表面活性剂的流.
- 在混合边界诱导局部协,形成无混合模板的微囊外.
- 研究了外可逆性和尺寸选择性透性.
主要成果:
- 在AOPS中实现了无模板的水在水微囊制造.
- 在富含表面活性剂的条件下产生均的微囊 (数百微米),具有长期稳定性.
- 经过证明的大小选择性透性,保留颗粒>500nm,同时允许较小的溶液扩散.
- 在性环境中展示了可逆的贝形成和溶解.
结论:
- 拟议的微流体战略为AOPS中微囊生产提供了一种简单,可扩展和环保的方法.
- 这种方法扩大了可持续的微囊设计和食品,制药和个人护理产品中高通量控制释放应用的可能性.
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