社会行为的进化转变与转录因子结合点的收和部分可逆扩展有关
Savanna G Ploessl1, Beryl M Jones1
1Department of Entomology, University of Kentucky, Lexington, KY 40546, USA.
Genome biology and evolution
|February 13, 2026
概括
蜜蜂的社会进化涉及基因调节的变化,转录因子 (TF) 动机在社会血统中扩大. 然而,当社交性丧失时,这些TF动机扩展不会逆转,这挑战了以前的假设.
科学领域:
- 进化生物学是进化的生物学.
- 基因组学就是基因组学.
- 行为生态学 行为生态学
背景情况:
- 昆虫,特别是蜜蜂的社会性,以繁殖分工为特征.
- 在共享基因组中的差异性基因调节是社会殖民地中独特的行为表型的基础.
- 转录因子 (TF) 结合基因被假设在社会进化过程中在基因调节的可塑性中发挥作用.
研究的目的:
- 调查转录因子 (TF) 动机扩张是否是跨蜜蜂血统社会进化的融合特征.
- 为了确定TF动机的存在是否减少,当社会行为是次要的损失.
- 确定特定的监管要素及其与社会性收益和损失相关的功能.
主要方法:
- 分析了42种不同的蜜蜂物种中基因促进体中预测的TF动机发生情况.
- 比较基因组学方法来追踪因子存在跨进化收益和社会性的损失.
- 统计分析以确定与社会演变相关的显著动机-促销者对变化.
主要成果:
- 确认了TF图案在已获得社交性的蜜蜂血统中扩展,这与之前的研究一致.
- 没有观察到二次失去了社会行为的血统中全基因组TF动机收缩.
- 确定了特定的动机,促进区域和动机-促进对,显示了具有社会收益和损失的互补变化.
结论:
- 与社交相关的新型表型可能来自现有的基因调节网络的修改.
- 虽然TF动机扩展伴随着社会性的增长,但它们的丧失并不是社会行为的次要丧失的一般特征.
- 确定了对特定生物体功能进行丰富的监管目标,为未来研究社会性的遗传基础提供了途径.
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