患者报告的结果测量可以预测神经群体的死亡率吗? 一个系统的审查
Hyunjun Ahn1, Yadi Li2, Nicolas Thompson2
1Lerner College of Medicine, Cleveland Clinic, Cleveland, OH, United States.
Frontiers in neurology
|February 13, 2026
概括
患者报告的结果测量 (PROM) 可以预测神经疾病中的死亡率. 身体健康PROM显示出比情绪性更强的预后价值,特别是在癌症和运动神经元疾病中.
科学领域:
- 神经学 神经学
- 临床流行病学临床流行病学
- 健康 结果 研究 研究 结果
背景情况:
- 患者报告的结果测量 (PROM) 对于监测症状和指导神经疾病的护理至关重要.
- 对于预测神经群体死亡率的PROMs的预后价值仍然不清楚.
- 本综述评估了PROMs在患有神经系统疾病的成年人中死亡率和生存率的预测能力.
研究的目的:
- 系统地审查和评估PROMs在预测死亡率和/或生存率方面的预后价值.
- 为了确定神经疾病和特定的PROMs与死亡率预测最强有力的证据.
- 探索不同神经疾病和PROM类型的预后效益的变化.
主要方法:
- 在 MEDLINE,Embase 和 Cochrane 中央注册 (2002-2024) 的系统文献搜索.
- 包括10个神经疾病中使用PROM预测死亡率/生存率的研究.
- 数据提取和偏差风险评估遵循PRISMA和CHARMS的指导方针;结果被描述性地总结.
主要成果:
- 49项研究符合纳入标准,重点研究中风,神经系统癌症和运动神经元疾病.
- 在75%的研究中,PROM独立预测死亡率,在神经系统癌症和运动神经元疾病中具有显著的效用.
- 通用PROMs (例如,SF-36) 和特定条件的PROMs (例如,EORTC QLQ) 显示出预后价值,身体健康组件更具预测性.
结论:
- 在各种神经疾病中,PROM对死亡率具有独立的预后价值.
- 预后效用根据特定的神经疾病和使用的PROM仪器不同.
- 进一步的研究应该调查PROMs在常规预后模型中的附加值和整合可行性.
相关概念视频
Predicting Reaction Outcomes
11.0K
Kinetics describes the rate and path by which a reaction occurs. In contrast, thermodynamics deals with state functions and describes the properties, behavior, and components of a system. It is not concerned with the path taken by the process and cannot address the rate at which a reaction occurs. Although it does provide information about what can happen during a reaction process, it does not describe the detailed steps of what appears on an atomic or a molecular level. On the other hand,...
11.0K
Uncertainty in Measurement: Accuracy and Precision
105.2K
Scientists typically make repeated measurements of a quantity to ensure the quality of their findings and to evaluate both the precision and the accuracy of their results. Measurements are said to be precise if they yield very similar results when repeated in the same manner. A measurement is considered accurate if it yields a result that is very close to the true or the accepted value. Precise values agree with each other; accurate values agree with a true value.
105.2K
Review and Preview
8.4K
In statistics, several tools are used to interpret the data. Measures of central tendency represent the characteristics of the data, such as mean, median, and mode. Additionally, measures of variance like standard deviation and range are used to find the spread of data from the mean. Relative standing measures the distance between data locations. Commonly used measures of relative standings are percentile, z score, and quartiles.
Percentiles are a type of fractile that partition data into...
Percentiles are a type of fractile that partition data into...
8.4K
Review and Preview
11.6K
Data are individual items of information obtained from a population or sample. Data may be classified as qualitative (categorical), quantitative continuous, or quantitative discrete. Because it is not practical to measure the entire population in a study, researchers use samples to represent the population. A random sample is a representative group from the population chosen by using a method that gives each individual in the population an equal chance of being included in the sample. Random...
11.6K
Data Reporting and Recording
5.5K
Reporting and recording are crucial in data documentation. The timely, thorough, and accurate documentation of facts is essential when recording patient data. Failure to record findings during an assessment or interpretation of a problem will result in loss of information and make the patient document unreliable. The reader is left with general impressions if the information is not specific. A recording is documenting data of the individual's health information in a traceable, secure, and...
5.5K
What is Population Genetics?
65.0K
A population is composed of members of the same species that simultaneously live and interact in the same area. When individuals in a population breed, they pass down their genes to their offspring. Many of these genes are polymorphic, meaning that they occur in multiple variants. Such variations of a gene are referred to as alleles. The collective set of all the alleles within a population is known as the gene pool.
65.0K


