预防性抗生素对K-Wire相关感染的影响:一个回顾性队列研究
Mohammad A Tahir1, Haroon Z Malik2, Sohail Nisar3
1Department of Emergency Medicine, Hull Royal Infirmary, Hull, GBR.
Cureus
|February 13, 2026
概括
预防性抗生素没有显著减少基尔施纳线 (K-线) 针部位在骨折固定中的感染. 这项研究没有发现支持常规抗生素使用的证据,强调需要进一步研究.
科学领域:
- 整形外科手术 整形外科手术
- 预防传染病 预防传染病
背景情况:
- 穿皮基尔施纳线 (K-线) 固定是骨折常见的.
- K-wire 针部位容易受到感染.
- 对预防性抗生素使用的证据是不确定的.
研究的目的:
- 为了确定预防性抗生素是否会降低K线针部位感染率.
- 为了比较接受和不接受预防的患者之间的感染发病率.
主要方法:
- 在两个中心进行的回顾性队列研究 (2007-2021年).
- 审查了264名患有K-wire固定器的患者,以治疗大腿骨或半径骨折.
- 收集了关于抗生素施用和针部位感染的数据.
主要成果:
- 总体而言,K线感染率为3.4%.
- 感染发病率为3.9%的预防 vs. 2.4%没有.
- 这一差异在统计学上并不显著 (p=0.73).
结论:
- 预防性抗生素没有观察到针部位感染率的降低.
- 由于感染率低,样本规模小,研究能力不足.
- 建议进一步进行随机对照试验,以告知临床实践.
更多相关视频
03:05Influence of Emotional Factors on the Efficacy of Acupuncture Treatment for Overweight Complicated with Hyperlipidemia: A Retrospective Cohort Study
Published on: November 21, 2025
650
05:53Candidate Gene Testing in Clinical Cohort Studies with Multiplexed Genotyping and Mass Spectrometry
Published on: June 21, 2018
10.8K
相关概念视频
Antibiotic Selection
60.2K
Overview
60.2K
Magnetic Field Due to Two Straight Wires
4.8K
Consider two parallel straight wires carrying a current of 10 A and 20 A in the same direction and separated by a distance of 20 cm. Calculate the magnetic field at a point "P2", midway between the wires. Also, evaluate the magnetic field when the direction of the current is reversed in the second wire.
4.8K
Household Wiring And Electrical Safety
1.7K
Companies that supply power to most modern households use three conductors, typically called a three-wire line. While one is neutral, the other two are both at 120 V but with opposite polarity, giving a voltage of 240 V between them. With a three-wire line, high-power appliances that require 240 V, such as electric stoves and clothes dryers, are linked between the two hot lines. 120 V appliances can be connected between the neutral and either of the hot lines. The neutral side, which is always...
1.7K
Magnetic Field Due To A Thin Straight Wire
6.3K
Consider an infinitely long straight wire carrying a current I. The magnetic field at point P at a distance a from the origin can be calculated using the Biot-Savart law.
6.3K
Magnetic Force On Current-Carrying Wires: Example
2.2K
In a magnetic field, moving charges encounter a force. If a wire contains these moving charges, i.e., if the wire is carrying a current, then a force acts on the wire as well. Consider a pair of flexible leads holding a wire that is 40 cm long and 10 g in weight in a horizontal position. The wire is placed in a constant magnetic field of 0.40 T, as shown in Figure 1(a). Determine the magnitude and direction of the current flowing in the wire needed to remove the tension in the supporting leads.
2.2K
Development of Antibiotic Resistance
1.6K
Antibiotic resistance is a major public health concern that arises when bacteria evolve mechanisms to withstand the effects of antibiotic treatments. This resistance can be intrinsic, acquired through genetic mutations, or transferred between bacteria via horizontal gene transfer. The development of antibiotic resistance poses significant challenges in treating bacterial infections and necessitates ongoing research to develop new therapeutic strategies.Intrinsic resistance occurs when bacterial...
1.6K
