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Updated: Feb 14, 2026

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在Stachybotrys chartarum中,具有未聚类基因的基灵梦的完整生物合成

Jimei Liu1, Ridao Chen1, Min Zhang1

  • 1State Key Laboratory of Bioactive Substance and Function of Natural Medicines, NHC Key Laboratory of Biosynthesis of Natural Products, CAMS Key Laboratory of Enzyme and Biocatalysis of Natural Drugs, and Beijing Key Laboratory of Non-Clinical Drug Metabolism and PK/PD Study, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China.

Acta pharmaceutica Sinica. B
|February 13, 2026
PubMed
概括

研究人员发现了stachybotrydial,一个phenylspirodrimane meroterpenoid的完整的生物合成途径. 这项研究确定了11个参与其形成的基因,并揭示了针对通道的潜在新药导向.

关键词:
生物合成生物合成表达式相关性分析表达式相关性分析层次的集群分析分析.甲基烯化物 (Meroterpenoid) 是一种烯化物.多个基因集群多个基因集群.菲尼尔spirodrimane 的使用情况.这种植物是Stachybotrys chartarum.没有聚类的基因.

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