在儿科中心工作十年:在气消化系统患者中检测食道病理和症状
Kaitlin Ballenger1, Anupama Kewalramani2, Lauren Bernard1
1University of Maryland School of Medicine, Baltimore, Maryland.
Gastro hep advances
|February 13, 2026
概括
在儿童中,性食道炎 (EoE) 和GERD往往表现出类似的症状,使得诊断变得困难. 空气消化评估对于识别食道疾病至关重要,即使是轻微的胃肠道疾病.
科学领域:
- 儿科胃肠病学 儿科胃肠病学
- 肺部病理学 肺部病理学
- 过敏和免疫学 过敏和免疫学
背景情况:
- 性食道炎 (EoE) 和胃食道逆流性疾病 (GERD) 分享重叠的症状,使儿科患者的诊断复杂化.
- 关于接受气消化评估的儿童的食道病理频率和相关症状的数据有限.
研究的目的:
- 在接受气消化评估的儿科患者中确定食道病理的频率.
- 为了比较患有EoE,GERD相关的食道炎和正常食道活检的儿童之间的症状学和支气管支气管洗 (BAL) 发现.
主要方法:
- 对126名儿科患者 (年龄在1-18岁) 的回顾性图表回顾,这些患者接受了食管胃管腺镜和支气管镜检查.
- 患者根据食道活检结果 (EoE,GERD相关的食道炎或正常) 进行分类.
- 分析了人口统计,症状和BAL细胞学,并在各组进行了比较.
主要成果:
- 21%的人患有EoE,25%的人患有与GERD相关的食道炎,59%的人进行了正常的活检.
- 与GERD或EOE患者相比,正常活检患者的胃肠道症状更为频繁.
- 在EoE患者中,像打这样的肺部症状更为普遍;BAL在EoE患者中显示出更高的乙氨基.
结论:
- 胃肠道和肺部症状不能可靠地预测儿童的食道病理.
- 历史性食道炎可以存在,尽管胃肠道的投诉很小,突出了基于症状的诊断的局限性.
- 空气消化评估对于诊断患有难治性呼吸道症状的儿科患者和识别食道疾病非常有价值.
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