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Updated: Feb 14, 2026

Molecular Profiling of the Invasive Tumor Microenvironment in a 3-Dimensional Model of Colorectal Cancer Cells and Ex vivo Fibroblasts
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在宫癌瘤微环境中,LAG-3相关的CD8+ T细胞功能障碍

Guang Zhang1,2, Lei Wang1,2, Jianhuan Chen1,2

  • 1Department of Gynecology, The First Afffliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, China.

Frontiers in immunology
|February 13, 2026
PubMed
概括

在宫癌中,含有T细胞免疫球蛋白和粘素域-3 (LAG-3) 的高度表达,与晚期和差异化相关. 拉格-3抑制CD8+T细胞的抗瘤功能,促进癌症的进展.

关键词:
CD8+ T T8+ CD8+ T T T8+ CD8+ T T8+ CD8+ CD8+ CD8+ T T T8+ CD8+ CD8+ CD8+ CD8+ CD8+ CD8+ T T T T免疫检查站检查站现场行动组-3宫癌:子宫癌是一种癌症.瘤微环境 (TME) 是指瘤的微环境.

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