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Updated: Feb 14, 2026

CRISPR/Cas9-mediated Targeted Integration In Vivo Using a Homology-mediated End Joining-based Strategy
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在溶液和活细胞中关闭CRISPR-Cas9活动的基于生物对称化学策略

Bhoomika Pandit1, Sweta Vangaveti2, Justa F Sentre1

  • 1Department of Chemistry, University at Albany, 1400 Washington Ave. Albany, NY 12208, United States.

NAR molecular medicine
|February 13, 2026
PubMed
概括

研究人员开发了一种新的小分子方法来控制CRISPR-Cas9基因编辑. 该系统使用生物对等化学来调节CRISPR-Cas9活动,为基因编辑应用提供精确的控制.

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