喉软骨瘤:一个SEER数据库分析分析
Ritu V Bhalerao1, Ashton Huppert Steed1, James Kelbert1
1University of Arizona College of Medicine-Phoenix, Phoenix, Arizona, USA.
The Laryngoscope
|February 13, 2026
概括
喉软骨瘤 (LC) 是罕见的,但具有良好的生存率. 器官保存手术,如部分切除,越来越多地比全喉切除 (TL) 更受青,以获得更好的结果.
科学领域:
- 在瘤学瘤学.
- 喉癌研究 喉癌研究
- 外科手术的结果
背景情况:
- 喉软骨瘤 (LC) 是一种非常罕见的恶性瘤,占所有喉癌症的不到1%.
- 目前的国家治疗策略和LC患者的治疗结果尚未明确,需要进行全面的分析.
研究的目的:
- 调查喉软骨瘤 (LC) 的发生率,存活率和治疗方式.
- 通过使用基于人口的数据,分析LC手术管理的国家趋势.
主要方法:
- 利用监测,流行病学和最终结果 (SEER) 数据库来识别2000年至2021年间被诊断患有LC的患者.
- 进行了卡普兰-梅尔生存分析和多变量考克斯回归以评估预后因素和治疗影响.
- 分析了351例确诊的LC病例的人口统计,治疗和生存数据.
主要成果:
- 喉软骨瘤 (LC) 占喉恶性瘤的0.3%,发现了351例.
- 在接受治疗的患者中,53.3%进行了器官保存手术 (局部切除/部分喉切除),而全喉切除 (TL) 则为27.5%.
- 十年疾病特异性存活率为84.8%;然而,晚期,老年和TL与多变量分析中较差的存活结果有关.
结论:
- 喉软骨瘤 (LC) 是罕见的,但表现出有利的长期存活率,趋向于器官保存手术方法.
- 部分切除越来越多地优先于全喉切除术 (TL),支持选择患者的器官保存.
- 患者的年龄和瘤阶段是关键的预后指标,而放射治疗起到最小的作用.
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