在中国,在患有或没有标准可修改心血管风险因素的患者中,ST片段升高心肌梗塞后的死亡率
Bin Sun1, Chunpo Liang1, Pengfei Sun1
1Department of Cardiology, Tianjin Medical University General Hospital, Tianjin Medical University, China (B.S., C.L., P.S., G.A., L.L., L.Z., P.L., Y.L., Q.Y., X.Z.).
Circulation. Population health and outcomes
|February 13, 2026
概括
没有标准可修改心血管风险因子 (SMuRF) 的患者接受ST段升高心肌梗塞治疗,面临更高的30天死亡率. 这种增加的风险仅限于事件发生后的最初一个月,后期死亡率没有显著差异.
科学领域:
- 心脏病学 心脏病学
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 没有标准可修改心血管风险因子 (SMuRF) 的ST段升高心肌梗塞 (STEMI) 患者的死亡率增加.
- 了解没有SMuRF的STEMI患者的特征和结果对于有针对性的干预至关重要.
研究的目的:
- 研究没有SMuRF的STEMI患者的临床特征,治疗方法和结果.
- 分析SMuRF-less状态和死亡率在一个大规模的全国性队列之间的关联.
主要方法:
- 一项全国性的多中心队列研究,使用来自中国心血管协会数据库-胸痛中心的数据.
- 包括2017-2021年期间入院的成年STEMI患者,将SMuRF定义为高血压,糖尿病,高脂血症或吸烟.
- 用多变量Cox回归和基准分析评估0-30天和31-365天的所有原因死亡率.
主要成果:
- 在379,811名STEMI患者中,有23.1%的患者没有SMuRF.
- 没有SMuRF的患者有更高的30天死亡率 (10.7%对6.7%),独立地与增加的风险相关 (aHR,1.22).
- 两组之间没有观察到31-365天死亡率的显著差异 (aHR,1.00),男性30天死亡率更高,男性30天死亡率更高.
结论:
- 在中国,近四分之一的STEMI病例是没有SMuRF的.
- 没有SMuRF的STEMI患者的过度死亡率主要集中在治疗后的前30天内.
- 在最初的30天后,SMuRF-less和SMuRF患者之间的后续死亡率没有显著差异.
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