老年高血压患者的动态血液动力学变化 接受Iopromide 370-Mediated冠状动脉CTA检查:一项前性对照试验
Lan Chen1, Heng Liu2, Junling Liu1
1Department of Radiology, Daping Hospital, Army Medical University, Yuzhong District, Chongqing.
Journal of computer assisted tomography
|February 13, 2026
概括
在老年高血压患者的冠状动脉计算机断层扫描血管造影 (CTA) 期间,Iopromide 370对比介质显示出有利的安全性. 血液动力学变化是暂时的,在不同组之间是可比的,尽管在高血压患者中更为明显.
科学领域:
- 心血管成像 - 心血管成像
- 放射学 放射学是一门学科.
- 药理学 药理学是指药理学的学科.
背景情况:
- 冠状动脉计算机断层扫描血管造影 (CTA) 对于诊断老年高血压患者冠状动脉心脏病至关重要.
- 了解对比介质的血液动力学影响对于患者的安全至关重要.
研究的目的:
- 在冠状动脉CTA期间注射有的对比剂后调查血液动力学变化.
- 评估老年高血压患者Iopromide 370的安全性和耐受性.
主要方法:
- 一项涉及32名高血压和32名非高血压患者的比较研究,这些患者接受了Iopromide 370.0的冠状动脉CTA治疗.
- 在6个时间点进行非侵入性血液动力学监测,从注射前到注射后30分钟.
- 使用独立样本t测试,奇二测试和重复测量ANOVA进行统计分析.
主要成果:
- 血液动力学变化是暂时的,在不同组之间是可比的,恢复到基线.
- 血动力学波动的幅度在高血压组中较大 (在基线的10%以内).
- 没有观察到急性过敏类反应;生理反应在各组之间没有显著差异.
结论:
- 伊奥普罗米德370在冠状动脉CTA中显示出良好的安全性和耐受性.
- 建议对患有心血管并发症的老年高血压患者提高临床谨慎性.
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