在图像导向乳腺活检中抗血栓治疗的管理:通过元分析进行系统性审查
Mario Villani1,2, Fabio Zecca1,3,4, Falko Ensle5
1Department of Breast Imaging, Gentofte Hospital, Hellerup (Copenhagen), Denmark.
Journal of breast imaging
|February 13, 2026
概括
在图像导向乳腺活检 (iBB) 期间继续抗血栓治疗 (AT) 是安全的. 虽然出血事件的频率略高,但它们通常是轻微的,在临床上无关紧要,避免了血栓栓塞事件的风险.
科学领域:
- 医学研究 医学研究
- 临床实践中的临床实践
- 干预性放射学是干预性的放射学.
背景情况:
- 抗血栓治疗 (AT) 对于预防血栓栓塞事件 (TEE) 至关重要.
- 关于出血事件 (BEs) 的担忧通常会导致在图像引导乳腺活检 (iBB) 之前停止AT治疗.
- 本研究评估了在iBB之前暂停AT的必要性和安全性.
研究的目的:
- 在图像引导乳腺活检 (iBB) 期间持续抗血栓治疗 (AT) 的必要性和安全性的系统审查和元分析.
- 与对照组相比,评估在AT时接受iBB的患者出血事件 (BEs) 的风险.
- 在iBB期间提供基于证据的AT管理建议.
主要方法:
- 在2024年7月之前对Embase和PubMed/MEDLINE数据库进行系统审查.
- 包括在患者接受iBB与AT.评估BEs的研究.
- 排除案例报告,调查和无法检索的全文;使用Review Manager v5.4.4 的数据分析.
主要成果:
- 八项包括1154名AT患者和10370名对照患者的研究符合纳入标准.
- 血液事件发生在17.9%的AT患者中,而对照组为10.7% (OR = 1.89,P < 0.001).
- 只有0.23%的BEs被认为是临床相关的,具有中等的异质性 (I2 = 34%).
结论:
- 在不暂停AT的情况下执行iBB得到了当前证据的支持,因为局部BEs主要是轻微的和临床上无关紧要的.
- 持续的AT提高了诊断效率,减少了延迟,最大限度地减少了患者的焦虑,降低了医疗保健成本.
- 继续AT解决了与中断相关的TEE风险,这是以前文献中经常被低估的因素.
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