圆度指数与女性不孕症之间的关联:来自NHANES的见解
Dong-Mei Tan1,2, Ping-Ping Cai3, Yi-Min Shi1,4
1Shandong University of Traditional Chinese Medicine, Jinan, PR China.
Medicine
|February 13, 2026
概括
较高的圆度指数 (C指数) 水平与女性不孕症风险增加有关. 这项研究表明,C指数可以帮助识别有风险的女性并管理肥胖,以减少不孕症的发生率.
科学领域:
- 生殖健康 生殖健康
- 内分泌学 在内分泌学.
- 公共卫生 公共卫生
背景情况:
- 肥胖是女性不孕症的一个已知的危险因素.
- 圆度指数 (C指数) 是衡量身体脂肪分布的指标,与女性不孕症的关系不清楚.
研究的目的:
- 调查C指数与女性不孕症之间的相关性.
- 探索C指数和不孕不育之间的剂量反应关系.
- 识别潜在的不孕症风险早期标志物.
主要方法:
- 利用了来自国家健康和营养检查调查 (2013-2018) 的数据.
- 通过生殖健康问卷评估女性不孕症.
- 使用多重物流回归和受限立方线分析来检查C指数关联.
主要成果:
- 总共分析了3496名女性,其中412名被诊断患有不孕症.
- 增加的C指数水平与更高的女性不育率显著相关 (OR: 1.80,95% CI: 1.25-2.59).
- 随着C指数的上升,观察到不孕不育率的逐渐增加,由脊柱分析证实 (整体P<0.001).
结论:
- 在美国女性中,C指数和女性不孕症之间存在积极的关系.
- "C指数"可以作为一种工具,用于早期识别有不孕症风险的女性.
- 以C指数为指导的肥胖管理可能会降低不孕率.
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