在国家癌症查计划中,在阳性FIT后结肠镜的诊断性能
Hyoung Il Choi1, Yunjin Joanne Yum, Hyewon Yang
1Department of Internal Medicine, Kyung Hee University Hospital at Gangdong, Kyung Hee University, Seoul, Republic of Korea.
Medicine
|February 13, 2026
概括
男性和标准便免疫化学测试 (FIT) 切断增加了结直肠癌查中的晚期瘤风险. 结肠镜检查的完成至关重要,特别是在FIT结果为阳性的男性中.
科学领域:
- 胃肠病学 胃肠病学
- 在瘤学瘤学.
- 公共卫生 公共卫生
背景情况:
- 韩国国家癌症查计划每年为50岁及以上的个人提供便免疫化学测试 (FIT).
- 评估FIT在检测晚期瘤 (AN) 的有效性对于优化查策略至关重要.
研究的目的:
- 评估FIT阳性后结肠镜的诊断性能.
- 确定具有FIT结果阳性的参与者中晚期瘤 (AN) 的患病率 (PR).
- 在这个人群中确定与AN相关的因素.
主要方法:
- 来自国家癌症查计划 (2007-2024) 数据的回顾性分析.
- 包括具有FIT阳性结果的参与者,根据性别,年龄,FIT切线和贫血来比较AN患病率.
- 多变量分析以确定AN的独立预测因子.
主要成果:
- 共有2445名参与者获得了FIT阳性结果;50.6%接受了结肠镜检查.
- 对AN的积极预测值为15.4%.
- 在男性 (PR=1.8) 和标准FIT切线 (PR=1.9) 中,AN患病率显著更高. 男性的性别和标准的FIT切断线独立地与AN相关.
结论:
- 晚期瘤在男性中更常见,在韩国查计划中使用标准FIT切断时更常见.
- 结肠镜完成率较低 (50.6%) 凸显了需要制定改善坚持治疗的策略.
- 针对男性和使用标准切线的FIT阳性结果的个人,为完成结肠镜检查提供了有针对性的建议.
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