健康的饮食模式,长寿基因和预期寿命:一个前性队列研究
Yanling Lv1,2, Jing Song3,4, Ding Ding5,6
1Department of Nutrition and Food Hygiene, Hubei Key Laboratory of Food Nutrition and Safety, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
Science advances
|February 13, 2026
概括
像糖尿病风险减轻饮食 (DRRD) 和替代地中海饮食 (AMED) 这样的健康饮食与更长的预期寿命有关. 采用这些饮食模式可以增加几年的寿命,无论遗传因素如何.
科学领域:
- 营养科学 营养科学
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 特定的健康饮食模式与长寿之间的关系尚未完全理解.
- 调查各种饮食指数对死亡率和预期寿命的影响对于公共卫生指导至关重要.
研究的目的:
- 检查五种不同的饮食模式与全因死亡率之间的潜在关联.
- 量化坚持这些饮食模式对大型队列中预期寿命的影响.
主要方法:
- 分析了来自103,649名英国生物库参与者的数据,平均随访时间为10.6年.
- 对五种饮食模式的评估:替代健康饮食指数-2010,替代地中海饮食 (AMED),健康的植物性饮食指数 (hPDI),停止高血压的饮食方法和降低糖尿病风险的饮食 (DRRD).
- 统计分析以确定与死亡率的关联,并计算增加的寿命年数,调整基因易感性.
主要成果:
- 所有五种评估的饮食模式都与减少全因死亡率和增加预期寿命有关.
- 糖尿病风险降低饮食 (DRRD) 和健康的植物性饮食指数 (hPDI) 显示了最强的关联.
- 坚持饮食分数的顶级五分之一与45岁时获得的额外1.53.0年的寿命相关,性别之间存在差异.
结论:
- 健康的饮食模式大大有助于增加预期寿命.
- 这些饮食在延长寿命方面的好处仍然存在,即使考虑到对长寿的遗传倾向.
- 促进对DRRD和AMED等饮食的坚持可以成为增长长寿的有价值的公共卫生战略.
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