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Updated: Feb 15, 2026

Stem-cell Based Engineered Immunity Against HIV Infection in the Humanized Mouse Model
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Published on: July 2, 2016

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在单次玻尿素免疫接种后,在 rhesus V2 apex knockin 鼠标模型中快速获得了 HIV-1 中和宽度

Amrit Raj Ghosh1, Rumi Habib2,3, Nitesh Mishra4,5

  • 1Batista Lab, Ragon Institute of Mass General Brigham, MIT, and Harvard, Cambridge, MA 02139, USA.

Science immunology
|February 13, 2026
PubMed
概括

在一只专门的小鼠模型中,用一种新型生殖线向型缩剂进行单次免疫接种,成功产生了针对HIV-1的广泛中和抗体 (bnAbs). 这种方法可能会简化未来的HIV疫苗开发.

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