系统性硬化症中的胃病:从系统性文献审查中获得的频谱,挑战和见解
Robert Mack Anderton1, Austin Zhu1, Ali Ayla2
1McGovern Medical School, Houston, TX, USA.
Seminars in arthritis and rheumatism
|February 13, 2026
概括
系统性硬化症 (SSc) 的胃并发症很常见,影响生活质量. 需要标准化诊断和患者报告的结果来改善SSc患者的护理.
科学领域:
- 胃肠病学 胃肠病学
- 类风湿病学 类风湿病学
- 内部医学 内部医学
背景情况:
- 胃部并发症在全身性硬化症 (SSc) 中很常见.
- 这些并发症显著影响患者的生活质量.
- 当前的诊断和管理策略往往是不充分的.
研究的目的:
- 审查有关SSc.胃表现的流行率和临床相关性的现有证据.
- 评估SSc相关的胃问题的诊断策略.
- 确定研究缺口,并提出未来的优先事项.
主要方法:
- 在遵守PRISMA指南的基础上进行系统审查.
- 在 MEDLINE,EMBASE 和 Web of Science 数据库中进行了搜索.
- 包括专注于SSc胃表现 (动力不良,GAVE,H. pylori) 和其影响或诊断的研究.
主要成果:
- 胃动力障碍 (延迟排空,勃拉迪加斯里亚) 非常普遍.
- 胃腹腔血管解脱症 (GAVE) 的患病率各不相同 (0-22.3%),并与特定抗体有关.
- 粘膜异常和Helicobacter pylori的患病率报告不一致;与患者结局的关联未得到充分研究.
结论:
- 在SSc中胃病是未被认可的,但在临床上是显著的.
- 标准化诊断 (光学图,呼吸测试,电胃图) 是至关重要的.
- 需要验证患者报告的结果和纵向研究,以优化护理和改善生活质量.
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