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Updated: Feb 15, 2026

Intranasal Administration of Recombinant Influenza Vaccines in Chimeric Mouse Models to Study Mucosal Immunity
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在小鼠中对一个8段的D型流感病毒进行临床前评估,作为一个活体减弱疫苗平台

Yiyu Xu1, Misa Katayama1, Hiroho Ishida2

  • 1Laboratory of Veterinary Microbiology, Department of Veterinary Medicine, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo, Japan.

Veterinary microbiology
|February 13, 2026
PubMed
概括

一种新的活衰减型D型流感病毒 (IDV) 候选疫苗,rD/OK-NS2ΔNOR,显示复制减少,并有效地保护小鼠免受牛呼吸系统疾病综合体 (BRDC) 的侵害. 这项临床前研究支持进一步对牛进行评估.

关键词:
复杂的牛呼吸道疾病综合体流感D型病毒感染者这是活体减弱疫苗.

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