用一种天然的小分子成本化物对HSP90进行向,以抑制亡和性结肠炎

Shan Yang1, Yunsen Zhang2, Yuying Shi3

  • 1College of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China; TCM Prevention and Treatment of Metabolic and Chronic Diseases Key Laboratory of Sichuan Province, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu 610075, China; Institute of High Altitude Multimorbidity/TCM-Integrated High-Altitude Medicine Center, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu 610075, China.

PubMed
概括

在性结肠炎 (UC) 模型中,costunolide (CTL) 通过准热冲击蛋白90 (HSP90) 来抑制亡. 这种新的治疗方法有效减少炎症和肠道损伤,为UC治疗提供了一个有前途的策略.

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