基于正念的减轻功能神经障碍的压力:可行性研究
Rosa Michaelis1, Jörg Meibert2, Nicole Alimov3
1Department of Neurology and Centre for Translational Neuro- and Behavioral Sciences (C-TNBS), University Medicine Essen, University of Duisburg-Essen, Essen, Germany; Department of Neurology, University Hospital Knappschaft Kliniken Bochum, Ruhr University Bochum, Bochum, Germany; Faculty of Health, University Witten/Herdecke, Witten, Germany.
Journal of psychosomatic research
|February 13, 2026
概括
基于正念的压力减轻 (MBSR) 是对功能神经障碍 (FND) 的可行和可接受的干预措施,显示了生活质量和功能障碍的改善. 需要进一步的试验来确认它的有效性.
科学领域:
- 神经学 神经学
- 精神病学是一个精神病学.
- 心灵与身体的干预
背景情况:
- 功能神经障碍 (FND) 具有显著的残疾,基于证据的治疗方法有限.
- 不适应的注意力过程与FND病理生理学有关,这表明正念干预可能是有益的.
- 基于正念的压力减轻 (MBSR) 对各种疾病有很好的支持,但其在FND中的应用尚未得到充分研究.
研究的目的:
- 评估一个为期8周的基于正念的压力减轻 (MBSR) 计划的可行性和可接受性,用于功能神经障碍 (FND) 的成年人.
- 评估MBSR干预FND患者后的初步临床结果,包括生活质量,功能障碍和症状负担.
主要方法:
- 一个单心,单臂的可行性研究,涉及诊断为FND的德语成年人.
- 参与者完成了一个标准化的8周的MBSR计划 (面对面和在线格式).
- 通过招聘,保留和出席来评估可行性;通过推概率来评估可接受性;通过验证的尺度来评估临床结果 (WHODAS 2.0,WSAS,PHQ-9,GAD-7,FNSQ).
主要成果:
- 该研究招募了57名符合条件的患者中的24名 (42%的招募率),具有很高的保留率 (92%) 和可接受性.
- 在干预后和随访时,观察到与健康相关的生活质量 (WHODAS 2.0) 和功能障碍 (WSAS) 的显著改善.
- 抑郁症症状 (PHQ-9) 和FND症状数量 (FNSQ) 的减少被注意到,而焦虑症 (GAD-7) 的变化没有显著. 在线交付显示了出色的坚持.
结论:
- 基于正念的压力减轻 (MBSR) 是一种可行且受欢迎的功能神经障碍 (FND) 患者的干预措施.
- 初步结果表明,对生活质量和功能障碍有潜在的益处.
- 建议进行随机对照试验,以确定MBSR对FND的疗效,这可能成为数字健康交付的模型.
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